Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 3/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | CPB1 | P15086 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL2846620 | 0.99 | KLK7 (0.39) | KLK7KLK5CASP3KEAP1NFE2L2 | |
| SCHEMBL2840948 | 0.91 | KLK7 (0.38) | KLK7KLK5CASP3KEAP1NFE2L2 | |
| SCHEMBL2848263 | 0.87 | KLK7 (0.44) | KLK7KLK5CASP3PTGER4 | |
| Hydrochloric Acid SCHEMBL2846241 | 0.84 | HDAC1 (0.43) | KLK7KLK5CASP3PTGER4FOLH1 | |
| SCHEMBL3622112 | 0.80 | PSMB5 (0.46) | KLK7KLK5CASP3FOLH1CPB1 | |
| SCHEMBL2844434 | 0.80 | MMP2 (0.48) | KLK7KLK5CASP3FOLH1DPP4 | |
| Hydrochloric Acid SCHEMBL2849314 | 0.80 | PSMB5 (0.45) | KLK7KLK5CASP3FOLH1CPB1 | |
| SCHEMBL2845511 | 0.80 | KLK7 (0.44) | KLK7KLK5CASP3PTGER4 | |
| SCHEMBL2849323 | 0.79 | CA1 (0.43) | KLK7KLK5CASP3PTGER4 | |
| SCHEMBL2840270 | 0.77 | CTSB (0.42) | KLK7KLK5CASP3PTGER4FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216803-A1 | ORNITHINE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2010-08-26 | — | — | US | disclosed |
| EP-2141147-A1 | ORNITHINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2010-01-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216803-A1 | ORNITHINE DERIVATIVE | PTGER4, OXER1, ODC1 | KLK7 2470/4885KLK5 1391/4885CASP3 3838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.