Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29791629 | 0.85 | MEN1 (0.41) | RAB9ANPC1NPSR1MEN1KMT2A | |
| SCHEMBL31388185 | 0.83 | ALDH1A1 (0.46) | HPGDLMNACYP2C19MEN1KMT2A | |
| SCHEMBL28435031 | 0.83 | GAA (0.45) | CYP1A2CYP3A4EPHB3ALDH1A1MAPT | |
| SCHEMBL1757402 | 0.83 | HTT (0.33) | PLAURAB9ANPC1HPGDHTT | |
| SCHEMBL30776547 | 0.83 | GAA (0.45) | CYP1A2CYP3A4EPHB3ALDH1A1MAPT | |
| SCHEMBL31388206 | 0.81 | ALDH1A1 (0.44) | HPGDLMNACYP2C19MEN1KMT2A | |
| SCHEMBL3936366 | 0.79 | KDR (0.54) | RAB9ANPC1HPGDHTTLMNA | |
| SCHEMBL4866567 | 0.79 | ALDH1A1 (0.46) | RAB9ANPC1HTTLMNANPSR1 | |
| SCHEMBL4865097 | 0.77 | POLB (0.40) | RAB9ANPC1HTTHDAC3HDAC4 | |
| SCHEMBL8141811 | 0.76 | MEN1 (0.39) | MEN1KMT2AALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105848685-B | Peptide mimetic compounds and antibody drug conjugates thereof | 健泰科生物技术公司 | 2020-09-22 | — | — | CN | disclosed |