Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28060559 | 0.83 | MAPT (0.40) | TSHRMAPTGAA | |
| SCHEMBL28058825 | 0.82 | PIK3CD (0.33) | TSHRMAPTGAA | |
| SCHEMBL28058833 | 0.82 | PIK3CD (0.33) | TSHRMAPTGAA | |
| SCHEMBL28060541 | 0.80 | NAMPT (0.35) | TSHRMAPTGAA | |
| SCHEMBL28060422 | 0.79 | PIK3CD (0.34) | TSHRMAPTGAA | |
| SCHEMBL27924339 | 0.77 | TP53 (0.34) | — | |
| SCHEMBL28278634 | 0.77 | TP53 (0.34) | — | |
| SCHEMBL28060551 | 0.77 | TP53 (0.34) | — | |
| SCHEMBL28055328 | 0.75 | SIGMAR1 (0.39) | — | |
| SCHEMBL27961259 | 0.73 | TSHR (0.31) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111662273-A | Preparation method of tyrosine kinase inhibitor AZD3759 | 通化师范学院 | 2020-09-15 | — | — | CN | claimed |
| CN-111662273-A | Preparation method of tyrosine kinase inhibitor AZD3759 | 通化师范学院 | 2020-09-15 | — | — | CN | disclosed |