SCHEMBL4397459

SCHEMBL4397459

COc1ccccc1/C=C/C(=O)c1cc2cc(Br)ccc2oc1=O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 4/20 0.65
MAOA P21397 5/20 0.62
KDM4E B2RXH2 2/20 0.56
MAPT P10636 2/20 0.56
HPGD P15428 2/20 0.56
RAB9A P51151 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
MAOB P27338 6/20 0.54
GRIN1 Q05586 1/20 0.51
GRIN2A Q12879 1/20 0.51
GRIN2B Q13224 1/20 0.51
GRIN2C Q14957 1/20 0.51
GPR35 Q9HC97 1/20 0.51
MEN1 O00255 1/20 0.51
ALDH1A1 P00352 1/20 0.51
LMNA P02545 1/20 0.51
POLB P06746 1/20 0.51
GAA P10253 1/20 0.51
PKM P14618 1/20 0.51
HTT P42858 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4397462 1.00 AR (0.65) ARMAOAKDM4EMAPTHPGD
SCHEMBL28458699 0.88 MAOB (0.69) ARMAOAKDM4EMAPTHPGD
SCHEMBL28458698 0.88 MAOB (0.69) ARMAOAKDM4EMAPTHPGD
SCHEMBL27092246 0.84 MAOB (0.77) ARMAOAKDM4EMAPTHPGD
SCHEMBL1368322 0.81 MAOA (0.76) MAOAKDM4EMAPTHPGDRAB9A
SCHEMBL1367747 0.81 MAOA (0.76) MAOAKDM4EMAPTHPGDRAB9A
SCHEMBL1367749 0.81 MAOA (0.76) MAOAKDM4EMAPTHPGDRAB9A
SCHEMBL4382617 0.78 GRIN1 (0.62) MAOAKDM4EMAPTHPGDSMN1; SMN2
SCHEMBL4382614 0.78 GRIN1 (0.62) MAOAKDM4EMAPTHPGDSMN1; SMN2
SCHEMBL31294094 0.78 GRIN1 (0.58) MAOAKDM4EMAPTHPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7629400-B2 Image making medium HYMAN SYDNEY 2009-12-08 US disclosed
US-20030035917-A1 Image making medium HYMAN SYDNEY (US) 2003-02-20 US disclosed