Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28455072 | 0.84 | PLA2G2A (0.58) | KDM4EALDH1A1MAPTCYP3A4TSHR | |
| SCHEMBL28458797 | 0.81 | KDM4E (0.47) | KDM4EALDH1A1MAPTCYP3A4CYP2C9 | |
| SCHEMBL28450673 | 0.78 | KMT2A (0.49) | KDM4EALDH1A1MAPTCYP3A4CYP2C9 | |
| SCHEMBL6244040 | 0.77 | MAPT (0.72) | KDM4EALDH1A1MAPTCYP3A4CYP2C9 | |
| SCHEMBL16378927 | 0.76 | KDM4E (0.50) | KDM4EALDH1A1MAPTCYP3A4CYP2C9 | |
| SCHEMBL28898265 | 0.76 | CYP2E1 (0.39) | KDM4EMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15676210 | 0.76 | MAPT (0.79) | KDM4EALDH1A1MAPTCYP3A4CYP2C9 | |
| SCHEMBL12413371 | 0.75 | KDM4E (0.67) | KDM4EALDH1A1MAPTCYP3A4CYP2C9 | |
| SCHEMBL28462269 | 0.74 | KDM4E (0.50) | KDM4EALDH1A1MAPTCYP3A4CYP2C9 | |
| SCHEMBL28466564 | 0.74 | RET (0.59) | KDM4EALDH1A1CYP3A4TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111635387-B | Synthesis method of chromone derivative | 都创(上海)医药科技股份有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-111635387-A | Synthesis method of chromone derivative | 都创(上海)医药科技有限公司 | 2020-09-08 | — | — | CN | disclosed |