Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | GABRP | O00591 | 2/20 | 0.48 |
| ▸ | GABRD | O14764 | 2/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.48 |
| ▸ | GABRE | P78334 | 2/20 | 0.48 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.48 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.48 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.48 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28455072 | 0.84 | PLA2G2A (0.58) | KMT2AKDM4ESMN1; SMN2LMNAPLA2G2A | |
| SCHEMBL28450669 | 0.81 | KMT2A (0.51) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL28458798 | 0.78 | KDM4E (0.48) | KMT2AKDM4ESMN1; SMN2LMNAPLA2G2A | |
| SCHEMBL30413690 | 0.76 | GABRP (0.54) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL1819136 | 0.76 | GABRP (0.54) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL1534555 | 0.76 | GABRP (0.55) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL1534564 | 0.75 | MAPT (0.46) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL28466564 | 0.74 | RET (0.59) | KMT2AKDM4ESMN1; SMN2LMNAPLA2G2A | |
| SCHEMBL28899237 | 0.74 | GABRP (0.50) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8860 | 0.73 | KDM4E (0.58) | KMT2AGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111635387-B | Synthesis method of chromone derivative | 都创(上海)医药科技股份有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-111635387-A | Synthesis method of chromone derivative | 都创(上海)医药科技有限公司 | 2020-09-08 | — | — | CN | disclosed |