Toluene

Toluene

SCHEMBL28459052

Cc1ccc(OP(=O)(O)Oc2ccc(C)cc2)cc1.Cc1ccccc1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.57
CYP3A4 P08684 1/20 0.57
SRC P12931 1/20 0.52
MEN1 O00255 6/20 0.51
KMT2A Q03164 6/20 0.51
LMNA P02545 4/20 0.51
MAPT P10636 1/20 0.51
NPSR1 Q6W5P4 1/20 0.50
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
ALDH1A1 P00352 2/20 0.46
PTK2B Q14289 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
HSP90AA1 P07900 1/20 0.45
GAA P10253 1/20 0.45
ALOX12 P18054 1/20 0.44
ACHE P22303 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL218003 0.96 CYP3A4 (0.57) TSHRCYP3A4SRCMEN1KMT2A
Toluene SCHEMBL26607511 0.94 SRC (0.59) TSHRCYP3A4SRCMEN1KMT2A
P-Xylene SCHEMBL8467418 0.94 SRC (0.59) TSHRCYP3A4SRCMEN1KMT2A
Biphenyl SCHEMBL17782089 0.92 CYP3A4 (0.53) TSHRCYP3A4SRCMEN1KMT2A
Toluene SCHEMBL29116599 0.92 SRC (0.57) TSHRCYP3A4SRCMEN1KMT2A
SCHEMBL157866 0.92 TSHR (0.67) TSHRCYP3A4SRCMEN1KMT2A
Toluene SCHEMBL29178514 0.90 SRC (0.55) TSHRCYP3A4SRCMEN1KMT2A
Naphthalene SCHEMBL15952534 0.90 CYP3A4 (0.55) TSHRCYP3A4SRCMEN1KMT2A
SCHEMBL5597386 0.90 TSHR (0.55) TSHRCYP3A4SRCMEN1KMT2A
Fluoride SCHEMBL31047203 0.90 TSHR (0.64) TSHRCYP3A4SRCMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111761772-A Preparation method of high-flame-retardant smoke-suppression LVT floor wear-resistant layer 宜宾天亿新材料科技有限公司 2020-10-13 CN claimed
CN-113603984-A Non-foaming flame-retardant anti-fogging PVC leather and preparation method and application thereof 广东天进新材料有限公司 2021-11-05 CN disclosed
CN-111423799-A Water-based polyurea coating material and preparation method thereof 沈阳化工研究院有限公司 2020-07-17 CN disclosed