Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL28459052 | 0.90 | TSHR (0.57) | TSHRCYP3A4MEN1KMT2ALMNA | |
| SCHEMBL218003 | 0.90 | CYP3A4 (0.57) | TSHRCYP3A4MEN1KMT2ALMNA | |
| SCHEMBL157866 | 0.90 | TSHR (0.67) | TSHRCYP3A4MEN1KMT2ALMNA | |
| Naphthalene SCHEMBL15952534 | 0.89 | CYP3A4 (0.55) | TSHRCYP3A4MEN1KMT2ALMNA | |
| P-Xylene SCHEMBL8467418 | 0.88 | SRC (0.59) | TSHRCYP3A4MEN1KMT2ALMNA | |
| SCHEMBL1983846 | 0.88 | TSHR (0.64) | TSHRCYP3A4MEN1KMT2ALMNA | |
| Fluoride SCHEMBL31047203 | 0.88 | TSHR (0.64) | TSHRCYP3A4MEN1KMT2ALMNA | |
| SCHEMBL8884790 | 0.88 | TSHR (0.64) | TSHRCYP3A4MEN1KMT2ALMNA | |
| Biphenyl SCHEMBL17782089 | 0.87 | CYP3A4 (0.53) | TSHRCYP3A4MEN1KMT2ALMNA | |
| Toluene SCHEMBL26607511 | 0.84 | SRC (0.59) | TSHRCYP3A4MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1245597-B1 | GRAFT COPOLYMER AND THERMOPLASTIC RESIN COMPOSITION CONTAINING THE SAME | MITSUBISHI RAYON CO (JP) | 2007-03-21 | — | — | EP | disclosed |
| US-6777492-B1 | GAS EVOLUTION DURING THE MOLDING IS REMARKABLY PREVENTED | MITSUBISHI RAYON CO., LTD. (JP) | 2004-08-17 | — | — | US | disclosed |
| EP-1245597-A1 | GRAFT COPOLYMER AND THERMOPLASTIC RESIN COMPOSITION CONTAINING THE SAME | Mitsubishi Rayon Co., Ltd. (JP) | 2002-10-02 | — | — | EP | disclosed |