Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.32 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.32 |
| ▸ | GSR | P00390 | 2/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725817 | 0.98 | GSR (0.36) | GSRPAOXCHRM1CHRM2CHRM4 | |
| SCHEMBL20703139 | 0.86 | GSR (0.38) | GSRPAOX | |
| SCHEMBL7885520 | 0.84 | PAOX (0.41) | PAOX | |
| SCHEMBL16252510 | 0.80 | PAOX (0.47) | PAOX | |
| SCHEMBL20547520 | 0.80 | THRB (0.37) | GSRPAOX | |
| SCHEMBL9512763 | 0.79 | CES2 (0.42) | GSRPAOXCHRM1CHRM2CHRM4 | |
| SCHEMBL24928356 | 0.79 | MEN1 (0.41) | GSR | |
| Hydrochloric Acid SCHEMBL14320525 | 0.79 | KDM4A (0.47) | PAOX | |
| SCHEMBL15759387 | 0.76 | TDP1 (0.44) | TDP1 | |
| SCHEMBL14685911 | 0.76 | PAOX (0.39) | GSRPAOXCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110431183-B | Hardenable multi-part acrylic composition | 三菱化学英国有限公司 | 2022-01-18 | — | — | CN | disclosed |
| CN-111629820-A | Hardenable multi-part acrylic composition | 璐彩特国际特殊聚合物和树脂有限公司 | 2020-09-04 | — | — | CN | disclosed |