Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 4/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F12 | P00748 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23183440 | 0.75 | ALDH1A1 (0.55) | ALDH1A1HTTPGRMAPTRAB9A | |
| SCHEMBL592819 | 0.75 | ALDH1A1 (0.55) | ALDH1A1HTTPGRMAPTRAB9A | |
| SCHEMBL18831876 | 0.75 | ALDH1A1 (0.55) | ALDH1A1HTTPGRMAPTRAB9A | |
| SCHEMBL23123770 | 0.75 | ALDH1A1 (0.38) | ALDH1A1HTTPGRF2F12 | |
| SCHEMBL29790069 | 0.75 | ALDH1A1 (0.38) | ALDH1A1HTTPGRF2F12 | |
| SCHEMBL22702884 | 0.73 | ALDH1A1 (0.40) | ALDH1A1HTTPGRF2F12 | |
| SCHEMBL22492538 | 0.72 | ALDH1A1 (0.54) | ALDH1A1HTTPGRF2F12 | |
| SCHEMBL1161494 | 0.70 | EGFR (0.33) | ALDH1A1MEN1KMT2AL3MBTL1EGFR | |
| SCHEMBL1093502 | 0.70 | HTR2A (0.37) | HTTMEN1KMT2AGAAMAPK1 | |
| SCHEMBL2639368 | 0.69 | CCKBR (0.33) | ALDH1A1MEN1KMT2AEGFRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111670034-A | Pyranopyrazoles and pyrazolopyridines immunomodulators for the treatment of autoimmune diseases | 洛克菲勒大学 | 2020-09-15 | — | — | CN | disclosed |