Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PDE5A | O76074 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28462514 | 0.95 | HTT (0.47) | EGFRMAPTKMT2AL3MBTL1LMNA | |
| SCHEMBL28462518 | 0.93 | EGFR (0.46) | EGFRMAPTKMT2AL3MBTL1CYP1A2 | |
| SCHEMBL28471314 | 0.90 | MEN1 (0.54) | EGFRMAPTKMT2AL3MBTL1LMNA | |
| SCHEMBL28466749 | 0.89 | PTGER4 (0.45) | EGFRALDH1A1HTTCTNNB1TCF7L2 | |
| SCHEMBL28465230 | 0.89 | S1PR3 (0.42) | EGFRMAPTKMT2AL3MBTL1LMNA | |
| SCHEMBL28465234 | 0.89 | EGFR (0.59) | EGFRMAPTKMT2AL3MBTL1LMNA | |
| SCHEMBL28460390 | 0.88 | EGFR (0.55) | EGFRMAPTKMT2AL3MBTL1PPARG | |
| SCHEMBL28463573 | 0.88 | LMNA (0.48) | EGFRMAPTKMT2APPARGLMNA | |
| SCHEMBL28462520 | 0.87 | CTNNB1 (0.58) | EGFRKMT2AL3MBTL1CYP1A2LMNA | |
| SCHEMBL28470826 | 0.86 | ALDH1A1 (0.54) | MAPTKMT2AL3MBTL1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107522659-B | 3-nitroquinoline derivative and preparation method and application thereof | 云南大学 | 2020-09-29 | — | — | CN | disclosed |