Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725364 | 0.90 | — | — | |
| SCHEMBL253527 | 0.90 | — | — | |
| SCHEMBL905194 | 0.90 | — | — | |
| Water SCHEMBL23295864 | 0.88 | ALDH1A1 (0.37) | ALDH1A1TSHRSMN1; SMN2MAPT | |
| Methane SCHEMBL8576129 | 0.88 | ALDH1A1 (0.37) | ALDH1A1TSHRSMN1; SMN2MAPT | |
| SCHEMBL27489343 | 0.88 | ALDH1A1 (0.37) | ALDH1A1TSHRSMN1; SMN2MAPT | |
| Sarcosine SCHEMBL27418475 | 0.82 | ALDH1A1 (0.33) | ALDH1A1MAPT | |
| Glycine SCHEMBL633951 | 0.81 | GLRA1 (0.37) | GLRA1SLC6A9OR51E2ALDH1A1TSHR | |
| SCHEMBL11691480 | 0.76 | — | — | |
| SCHEMBL3205794 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111518625-A | Acidic cleaning agent and preparation method and application thereof | 广东环凯生物技术有限公司 | 2020-08-11 | — | — | CN | disclosed |