Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.32 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6533341 | 0.82 | — | — | |
| Glycine SCHEMBL28459694 | 0.81 | GLRA1 (0.37) | GLRA1SLC6A9OR51E2ALDH1A1TSHR | |
| Glycine SCHEMBL28337203 | 0.74 | — | — | |
| Acetic Acid SCHEMBL1160860 | 0.72 | SLC6A4 (0.36) | ALDH1A1TSHRSMN1; SMN2MAPT | |
| SCHEMBL5570056 | 0.71 | SLC6A4 (0.38) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL253527 | 0.70 | — | — | |
| SCHEMBL905194 | 0.70 | — | — | |
| SCHEMBL725364 | 0.70 | — | — | |
| SCHEMBL1551333 | 0.69 | MAPT (0.35) | HPGDHSD17B10ALDH1A1TSHRSMN1; SMN2 | |
| Water SCHEMBL23295864 | 0.68 | ALDH1A1 (0.37) | HPGDHSD17B10ALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2420141-B1 | Methods of reducing phytotoxicity of a pesticide | ORO AGRI INC (US) | 2016-10-12 | — | — | EP | claimed |
| WO-2012074486-A1 | MILK-BASED PESTICIDAL FORMULATION | ORO AGRI INTERNATIONAL LTD (KY) | 2012-06-07 | — | — | WO | claimed |
| EP-2420141-A1 | Methods of reducing phytotoxicity of a pesticide | Oro Agri, Inc (US) | 2012-02-22 | — | — | EP | claimed |
| US-20240116831-A1 | Methods and Compositions for Soil Regeneration and Improved Soil Hydrology | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2024-04-11 | — | — | US | disclosed |
| WO-2023069313-A1 | METHODS AND COMPOSITIONS FOR SOIL REGENERATION AND IMPROVED SOIL HYDROLOGY | LOCUS SOLUTIONS IPCO, LLC (US) | 2023-04-27 | — | — | WO | disclosed |
| US-20210276929-A1 | MICROBIAL SOIL ENHANCEMENT | LE KHANH (US) | 2021-09-09 | — | — | US | disclosed |
| US-20210230081-A1 | MICROBIAL SOLUTION | LE KHANH (US) | 2021-07-29 | — | — | US | disclosed |
| US-10899676-B2 | Animal feed stock using microbial enhancement | Cisbay Global Inc. (US) | 2021-01-26 | — | — | US | disclosed |
| US-20200189988-A1 | ANIMAL FEED STOCK USING MICROBIAL ENHANCEMENT | LE KHANH (US) | 2020-06-18 | — | — | US | disclosed |
| US-20200079703-A1 | SOIL ENHANCEMENT | LE KHANH (US) | 2020-03-12 | — | — | US | disclosed |
| US-20200055793-A1 | SOIL ENHANCEMENT | LE KHANH (US) | 2020-02-20 | — | — | US | disclosed |
| US-20100144534-A1 | Compositions and methods for the control of nematodes and soil borne diseases | ORO AGRI, INC. | 2010-06-10 | — | — | US | disclosed |
| EP-1344528-B1 | EXTERNAL SKIN PREPARATIONS AND PROCESS FOR PRODUCING THE SAME | YAKULT HONSHA KK (JP) | 2008-10-08 | — | — | EP | disclosed |
| WO-2008097553-A2 | CITRUS OIL COMPOSITIONS AND METHODS OF USE | ORO AGRI, INC. (US) | 2008-08-14 | — | — | WO | disclosed |
| US-7090875-B2 | External skin preparations and process for producing the same | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2006-08-15 | — | — | US | disclosed |
| EP-1285661-B1 | USE OF AN ANTIOXIDANT COMPRISING AN EXTRACT OF MOZUKU | YAKULT HONSHA KK (JP) | 2006-06-14 | — | — | EP | disclosed |
| US-20040057913-A1 | Antioxidant and skin preparations for external use | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2004-03-25 | — | — | US | disclosed |
| US-20040029829-A1 | External skin preparations and process for producing the same | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2004-02-12 | — | — | US | disclosed |
| EP-1344528-A1 | EXTERNAL SKIN PREPARATIONS AND PROCESS FOR PRODUCING THE SAME | Kabushiki Kaisha Yakult Honsha (JP) | 2003-09-17 | — | — | EP | disclosed |
| EP-1285661-A1 | ANTIOXIDANT AND SKIN PREPARATIONS FOR EXTERNAL USE | Kabushiki Kaisha Yakult Honsha (JP) | 2003-02-26 | — | — | EP | disclosed |