Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 4/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.42 |
| ▸ | FAAH | O00519 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28461072 | 1.00 | CHRNB4 (0.42) | CHRNB4CHRNA3FAAHALDH1A1KDM4E | |
| SCHEMBL15607421 | 0.97 | ALDH1A1 (0.39) | CHRNB4CHRNA3FAAHALDH1A1KDM4E | |
| SCHEMBL6205627 | 0.87 | CHRNB4 (0.57) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNB3 | |
| SCHEMBL5240331 | 0.87 | CHRNB4 (0.57) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNB3 | |
| SCHEMBL28311169 | 0.85 | FAAH (0.43) | CHRNB4CHRNA3FAAHKDM4ECYP2D6 | |
| SCHEMBL28875445 | 0.84 | CHRNB4 (0.42) | CHRNB4CHRNA3FAAHALDH1A1KDM4E | |
| SCHEMBL620438 | 0.84 | KDM4E (0.42) | CHRNB4CHRNA3FAAHALDH1A1KDM4E | |
| SCHEMBL28311231 | 0.84 | CHRNB4 (0.42) | CHRNB4CHRNA3FAAHALDH1A1KDM4E | |
| SCHEMBL28875444 | 0.84 | CHRNB4 (0.42) | CHRNB4CHRNA3FAAHALDH1A1KDM4E | |
| SCHEMBL28311232 | 0.84 | CHRNB4 (0.42) | CHRNB4CHRNA3FAAHALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107365319-B | Modulation of chemosensory receptors and ligands associated therewith | 弗门尼舍公司 | 2020-10-27 | — | — | CN | disclosed |
| CN-106107406-B | Methods of improving the stability of sweetness enhancers and compositions comprising stable sweetness enhancers | 弗门尼舍公司 | 2020-06-09 | — | — | CN | disclosed |