Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26930413 | 0.79 | ATM (0.37) | KDM4EHPGDALDH1A1HSD17B10AGTR1 | |
| SCHEMBL15762047 | 0.76 | KDM4E (0.51) | KDM4EHPGDALDH1A1POLBLMNA | |
| SCHEMBL15130954 | 0.73 | KDM4E (0.48) | KDM4EHPGDALDH1A1POLBLMNA | |
| SCHEMBL30344008 | 0.72 | POLB (0.64) | KDM4EHPGDALDH1A1POLBLMNA | |
| SCHEMBL1180653 | 0.72 | POLB (0.64) | KDM4EHPGDALDH1A1POLBLMNA | |
| SCHEMBL28979723 | 0.70 | POLB (0.48) | KDM4EALDH1A1POLBLMNAAGTR1 | |
| SCHEMBL28051926 | 0.70 | KDM4E (0.58) | KDM4EHPGDALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL996292 | 0.69 | ABCB1 (0.50) | KDM4EALDH1A1POLBLMNAAGTR1 | |
| SCHEMBL27700924 | 0.69 | AGTR1 (0.50) | KDM4EHPGDALDH1A1POLBLMNA | |
| SCHEMBL21803763 | 0.68 | HDAC1 (0.37) | KDM4EHPGDALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484438-B | Polysubstituted indole derivative and metal catalysis preparation method thereof | 湖北科技学院 | 2023-02-03 | — | — | CN | disclosed |
| CN-111484438-A | Polysubstituted indole derivative and metal catalysis preparation method thereof | 湖北科技学院 | 2020-08-04 | — | — | CN | disclosed |