SCHEMBL2846124

SCHEMBL2846124

Cc1cc(I)c(S(=O)(=O)O)cc1I

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 2/20 0.34
MYC P01106 1/20 0.32
TP53 P04637 1/20 0.32
CREBBP Q92793 1/20 0.32
POLB P06746 2/20 0.31
RECQL P46063 2/20 0.31
SUMO2 P61956 1/20 0.31
SUMO1 P63165 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP3 Q9H4L4 1/20 0.31
SENP2 Q9HC62 1/20 0.31
SENP1 Q9P0U3 1/20 0.31
ESR2 Q92731 1/20 0.31
TET2 Q6N021 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
CASP6 P55212 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2842600 0.91 BRD4 (0.34) BRD4MYCTP53CREBBPPOLB
SCHEMBL4565243 0.86 TET2 (0.35) MYCTET2ALDH1A1TDP1LMNA
SCHEMBL2844078 0.74 HTR2A (0.39) TP53POLBRECQLKDM4EMEN1
SCHEMBL32679848 0.72 ALDH1A1 (0.39) MYCPOLBRECQLKDM4EMEN1
SCHEMBL12993995 0.72 POLB (0.43) BRD4MYCTP53CREBBPPOLB
SCHEMBL24278496 0.72 ALDH1A1 (0.39) MYCPOLBRECQLTET2KDM4E
SCHEMBL360272 0.72 ALDH1A1 (0.39) MYCPOLBRECQLKDM4EMEN1
SCHEMBL1685558 0.72 TTR (0.37) TP53ALDH1A1TDP1
SCHEMBL2848985 0.71 TET2 (0.41) TET2LMNAHPGDHIF1AHSD17B10
SCHEMBL197382 0.71 RAD51 (0.41) TET2LMNAHPGDHIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120251919-A1 POLYARYLENE-BASED COPOLYMER AND USES THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-04 US disclosed
EP-2489690-A1 POLYARYLENE COPOLYMER AND USES THEREOF Sumitomo Chemical Company Limited (JP) 2012-08-22 EP disclosed
US-20100129729-A1 CEOSSLINKED AROMATIC POLYMER, POLYMER ELECTROLYTE,CATALYST INK, POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTRODE ASSEMBLY AND FUEL CELL SUMITOMO CHEMICAL COMPANY ,LIMITED 2010-05-27 US disclosed
EP-2147943-A1 CROSSLINKED AROMATIC POLYMER, POLYMER ELECTROLYTE, CATALYST INK, POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTRODE ASSEMBLY AND FUEL CELL Sumitomo Chemical Company, Limited (JP) 2010-01-27 EP disclosed
US-20090253015-A1 POLYARYLENE BLOCK COPOLYMER AND USE THEREOF SUMITOMO CHEMICAL COMPANY ,LIMITED (JP) 2009-10-08 US disclosed
EP-1857482-A1 POLYARYLENE BLOCK COPOLYMER AND USE THEREOF Sumitomo Chemical Company, Limited (JP) 2007-11-21 EP disclosed