Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.31 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2846124 | 0.86 | BRD4 (0.34) | TET2HSD17B10ALDH1A1TDP1LMNA | |
| SCHEMBL197382 | 0.83 | RAD51 (0.41) | TET2HSD17B10TTRCA1CA2 | |
| SCHEMBL2848985 | 0.83 | TET2 (0.41) | TET2HSD17B10TTRCA1CA2 | |
| SCHEMBL2842600 | 0.81 | BRD4 (0.34) | TET2HSD17B10ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL2844078 | 0.81 | HTR2A (0.39) | HSD17B10ALDH1A1TDP1TSHRSMN1; SMN2 | |
| SCHEMBL2840799 | 0.78 | HPGD (0.34) | TET2HSD17B10ALDH1A1TDP1TTR | |
| SCHEMBL18066938 | 0.78 | LMNA (0.50) | TET2HSD17B10ALDH1A1TDP1CASP1 | |
| SCHEMBL19730666 | 0.78 | PGAM1 (0.46) | TET2HSD17B10ALDH1A1TDP1CASP1 | |
| SCHEMBL1619161 | 0.76 | TET2 (0.37) | TET2HSD17B10CA1CA2CA9 | |
| SCHEMBL2840569 | 0.76 | ALDH1A1 (0.38) | HSD17B10ALDH1A1TDP1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090259013-A1 | LIQUID CRYSTAL POLY(PHENYLENE DISULFONIC ACIDS) | CASE WESTERN RESERVE UNIVERSITY | 2009-10-15 | — | — | US | disclosed |