Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 3/20 | 0.64 |
| ▸ | RHEB | Q15382 | 10/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23147975 | 0.83 | IDO1 (0.47) | GRIN1RHEBMEN1CYP2C9HPGD | |
| SCHEMBL23148145 | 0.81 | RHEB (0.49) | GRIN1RHEBKDM4ELMNAEIF4A3 | |
| SCHEMBL1144772 | 0.80 | GRIN1 (0.72) | GRIN1RHEBMEN1CYP2C9HPGD | |
| SCHEMBL30310414 | 0.80 | GRIN1 (0.72) | GRIN1RHEBMEN1CYP2C9HPGD | |
| SCHEMBL28455744 | 0.79 | ALOX15 (0.55) | GRIN1RHEBMEN1HPGDKMT2A | |
| SCHEMBL727389 | 0.78 | GRIN1 (1.00) | GRIN1RHEBMEN1CYP2C9HPGD | |
| SCHEMBL29531428 | 0.78 | GRIN1 (1.00) | GRIN1RHEBMEN1CYP2C9HPGD | |
| SCHEMBL6448130 | 0.78 | RHEB (0.52) | GRIN1RHEBHPGDKDM4EEIF4A3 | |
| SCHEMBL13956187 | 0.77 | GRIN1 (0.72) | GRIN1RHEBMEN1CYP2C9HPGD | |
| SCHEMBL30310417 | 0.76 | KDM4E (0.53) | GRIN1RHEBMEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107098846-B | N-acyl sulfonamide FBPase inhibitor, preparation method thereof, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2020-10-09 | — | — | CN | disclosed |