SCHEMBL28461553

SCHEMBL28461553

CCCCCCCCCCCCCCCCCCCCOc1cc(Br)c(Br)cc1OCCCCCCCCCCCCCCCCCCCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 4/20 0.47
THRB P10828 4/20 0.47
SMPD1 P17405 4/20 0.46
SMN1; SMN2 Q16637 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
S1PR3 Q99500 2/20 0.43
PTPN11 Q06124 1/20 0.43
CYSLTR2 Q9NS75 1/20 0.43
CYSLTR1 Q9Y271 1/20 0.43
TLR8 Q9NR97 1/20 0.42
NR5A1 Q13285 1/20 0.42
MEN1 O00255 1/20 0.42
NR1I2 O75469 1/20 0.42
LMNA P02545 1/20 0.42
CHRM2 P08172 1/20 0.42
CYP3A4 P08684 1/20 0.42
ADRA2A P08913 1/20 0.42
MAPT P10636 1/20 0.42
OPRK1 P41145 1/20 0.42
HTR2B P41595 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21051152 1.00 THRA (0.47) THRATHRBSMPD1SMN1; SMN2NPSR1
SCHEMBL30695615 1.00 THRA (0.47) THRATHRBSMPD1SMN1; SMN2NPSR1
SCHEMBL28034495 1.00 THRA (0.47) THRATHRBSMPD1SMN1; SMN2NPSR1
SCHEMBL28463496 0.98 THRA (0.46) THRATHRBSMPD1SMN1; SMN2NPSR1
SCHEMBL28458815 0.96 THRA (0.45) THRATHRBSMPD1SMN1; SMN2NPSR1
SCHEMBL2053781 0.91 THRA (0.49) THRATHRBSMPD1SMN1; SMN2NPSR1
SCHEMBL197292 0.91 THRA (0.49) THRATHRBSMPD1SMN1; SMN2NPSR1
SCHEMBL339687 0.91 THRA (0.49) THRATHRBSMPD1SMN1; SMN2NPSR1
SCHEMBL339836 0.91 THRA (0.49) THRATHRBSMPD1SMN1; SMN2NPSR1
SCHEMBL2049161 0.91 THRA (0.49) THRATHRBSMPD1SMN1; SMN2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111732839-A Phthalocyanine D-pi-A type asymmetric disc dye and preparation method thereof 南京优写智能科技有限公司 2020-10-02 CN claimed
CN-111732839-B Phthalocyanine D-Pi-A type asymmetric disc-shaped dye and preparation method thereof 苏州优特创优新材料科技有限公司 2022-05-13 CN disclosed
CN-111732839-A Phthalocyanine D-pi-A type asymmetric disc dye and preparation method thereof 南京优写智能科技有限公司 2020-10-02 CN disclosed