SCHEMBL197292

SCHEMBL197292

CCCCCCOc1cc(Br)c(OCCCCCC)cc1Br

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 4/20 0.49
THRB P10828 4/20 0.49
S1PR3 Q99500 2/20 0.45
S1PR2 O95136 1/20 0.45
S1PR1 P21453 1/20 0.45
LPAR2 Q9HBW0 1/20 0.45
SMPD1 P17405 4/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
PTPN11 Q06124 1/20 0.43
CYSLTR2 Q9NS75 1/20 0.43
CYSLTR1 Q9Y271 1/20 0.43
TLR8 Q9NR97 1/20 0.42
NR5A1 Q13285 1/20 0.42
MEN1 O00255 1/20 0.42
NR1I2 O75469 1/20 0.42
LMNA P02545 1/20 0.42
CHRM2 P08172 1/20 0.42
CYP3A4 P08684 1/20 0.42
ADRA2A P08913 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL339836 1.00 THRA (0.49) THRATHRBS1PR3S1PR2S1PR1
SCHEMBL339687 1.00 THRA (0.49) THRATHRBS1PR3S1PR2S1PR1
SCHEMBL2049161 1.00 THRA (0.49) THRATHRBS1PR3S1PR2S1PR1
SCHEMBL2053781 1.00 THRA (0.49) THRATHRBS1PR3S1PR2S1PR1
SCHEMBL2038965 0.98 THRA (0.47) THRATHRBS1PR3S1PR2S1PR1
SCHEMBL25340169 0.94 THRA (0.48) THRATHRBS1PR3S1PR2S1PR1
SCHEMBL3854108 0.92 THRA (0.48) THRATHRBS1PR3S1PR2S1PR1
SCHEMBL3858144 0.92 THRA (0.48) THRATHRBS1PR3S1PR2S1PR1
SCHEMBL3852512 0.92 THRA (0.45) THRATHRBS1PR3S1PR2S1PR1
SCHEMBL4604305 0.92 SMPD1 (0.49) THRATHRBS1PR3S1PR2S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8525131-B2 Phosphorescent organic compounds THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2013-09-03 US claimed
US-20120248337-A1 PHOSPHORESCENT ORGANIC COMPOUNDS THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2012-10-04 US claimed
WO-2011066415-A2 PHOSPHORESCENT ORGANIC COMPOUNDS THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2011-06-03 WO claimed
WO-2025121285-A1 PHOSPHINE-PALLADIUM COMPLEX, POLYMERIZATION CATALYST, AND METHOD FOR PRODUCING AROMATIC POLYMER 日本化学工業株式会社 2025-06-12 WO disclosed
CN-114874251-A Silicon center chiral silanol and synthetic method thereof 南方科技大学 2022-08-09 CN disclosed
CN-110003271-B Process for producing aromatic compound 住友化学株式会社 2022-05-03 CN disclosed
US-11045796-B2 Process for producing aromatic compound, and palladium complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-06-29 US disclosed
CN-108368142-B Method for producing aromatic compound and palladium complex 住友化学株式会社 2021-02-19 CN disclosed
WO-2020200681-A1 POLYMERIZATION METHOD RHEINISCH-WESTFÄLISCHE TECHNISCHE HOCHSCHULE (RWTH) AACHEN (DE) 2020-10-08 WO disclosed
CN-107759775-B Donor-receptor type alternating polymer containing sulfone-based fused ring structure and having strong two-photon effect, preparation method and application 华南协同创新研究院 2020-06-05 CN disclosed
US-20180369799-A1 PROCESS FOR PRODUCING AROMATIC COMPOUND, AND PALLADIUM COMPLEX SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-12-27 US disclosed
US-20030161605-A1 Nonlinear optical chiral compounds and devices incorporating same KVH INDUSTRIES, INC. 2003-08-28 US disclosed
US-20030091859-A1 Fluorene compounds containing various functional groups, polymers thereof and el element using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2003-05-15 US disclosed
WO-2003003112-A1 NONLINEAR OPTICAL CHIRAL COMPOUNDS AND DEVICES INCORPORATING SAME KVH INDUSTRIES, INC. (US) 2003-01-09 WO disclosed
US-6344286-B1 CONTAINING FLUORENE, CARBAZOLE AND/OR BENZENE GROUPS HANWHA CHEMICAL CORPORATION (KR) 2002-02-05 US disclosed
US-6020452-A Chiral biphenyl compounds for use in asymmetric reactions NORTH DAKOTA STATE UNIVERSITY (US) 2000-02-01 US disclosed
US-5889134-A POLYMER BASED ON A ROTATION-HINDERED 2,2'SUBSTITUTED BIPHENYL SUBUNIT WHICH WHEN REACTED WITH AN ORGANOZINC COMPOUND CATALYZES KETONE REDUCTION BY A BORANE, EPOXIDATION OF AN A,B-UNSATURATED COMPOUND USING OXYGEN; ALDEHYDE ALKYLATION NORTH DAKOTA STATE UNIVERSITY (US) 1999-03-30 US disclosed
US-5876864-A Fluorene-based alternating polymers containing acetylene group and electroluminescence element using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY 1999-03-02 US disclosed
US-5653914-A Electroluminescent device comprising a chromophoric polymeric composition CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 1997-08-05 US disclosed
WO-1994015441-A1 ELECTROLUMINESCENT DEVICE COMPRISING A CHROMOPHORIC POLYMERIC COMPOSITION CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 1994-07-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11045796-B2 Process for producing aromatic compound, and palladium complex DDT, DRD1, DRD2 THRA 3752/4885THRB 2911/4885S1PR3 3348/4885
US-20120248337-A1 PHOSPHORESCENT ORGANIC COMPOUNDS PAICS, PPIP5K2, PPA1 THRA 3970/4885THRB 4281/4885S1PR3 4408/4885
US-20030091859-A1 Fluorene compounds containing various functional groups, polymers thereof and el element using the same AFF4, AFF2, LEF1 THRA 3513/4885THRB 4416/4885S1PR3 4045/4885
US-20180369799-A1 PROCESS FOR PRODUCING AROMATIC COMPOUND, AND PALLADIUM COMPLEX DDT, DRD1, DRD2 THRA 3752/4885THRB 2911/4885S1PR3 3348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.