Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28144670 | 0.80 | TDP1 (0.47) | MAPTLMNAHSD17B10HTTRAB9A | |
| SCHEMBL13662746 | 0.80 | MAPT (0.56) | MAPTLMNAPTGS2HTTRAB9A | |
| SCHEMBL28457496 | 0.80 | LMNA (0.36) | MAPTLMNAHSD17B10PTGS2HTT | |
| SCHEMBL11348738 | 0.79 | ALDH1A1 (0.61) | MAPTLMNAHTTMEN1KMT2A | |
| SCHEMBL13659761 | 0.79 | NOTUM (0.46) | MAPTLMNAHTTRAB9AMEN1 | |
| SCHEMBL4895319 | 0.79 | MAPT (0.59) | MAPTLMNAHSD17B10PTGS2HTT | |
| Fenamole SCHEMBL43680 | 0.79 | ALDH1A1 (0.53) | MAPTLMNAHTTRAB9AMEN1 | |
| SCHEMBL28463371 | 0.79 | POLB (0.47) | MAPTLMNAHTTMEN1TP53 | |
| SCHEMBL5685523 | 0.76 | MAPT (0.56) | MAPTLMNAHSD17B10PTGS2HTT | |
| SCHEMBL10402398 | 0.76 | MAPT (0.56) | MAPTLMNAHSD17B10PTGS2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107501198-B | Sulfoxide tetrazole derivative and preparation method and application thereof | 南京农业大学 | 2020-08-18 | — | — | CN | disclosed |