Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.58 |
| ▸ | TLR2 | O60603 | 2/20 | 0.57 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.57 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.57 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.56 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.55 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.55 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.55 |
| ▸ | RRM1 | P23921 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | GGT1 | P19440 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | FURIN | P09958 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.43 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28385127 | 1.00 | NOD1 (0.58) | NOD1TLR2SIRT6SIRT1SLC6A5 | |
| SCHEMBL31042212 | 1.00 | NOD1 (0.58) | NOD1TLR2SIRT6SIRT1SLC6A5 | |
| SCHEMBL2050730 | 1.00 | NOD1 (0.58) | NOD1TLR2SIRT6SIRT1SLC6A5 | |
| SCHEMBL31042213 | 1.00 | NOD1 (0.58) | NOD1TLR2SIRT6SIRT1SLC6A5 | |
| SCHEMBL31050906 | 1.00 | NOD1 (0.58) | NOD1TLR2SIRT6SIRT1SLC6A5 | |
| SCHEMBL285285 | 1.00 | NOD1 (0.58) | NOD1TLR2SIRT6SIRT1SLC6A5 | |
| SCHEMBL9791228 | 1.00 | NOD1 (0.58) | NOD1TLR2SIRT6SIRT1SLC6A5 | |
| SCHEMBL7460571 | 1.00 | NOD1 (0.58) | NOD1TLR2SIRT6SIRT1SLC6A5 | |
| SCHEMBL199411 | 1.00 | NOD1 (0.58) | NOD1TLR2SIRT6SIRT1SLC6A5 | |
| SCHEMBL2701831 | 1.00 | NOD1 (0.58) | NOD1TLR2SIRT6SIRT1SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111683672-A | Modulators of complement activity | RA制药公司 | 2020-09-18 | — | — | CN | disclosed |