SCHEMBL199411

SCHEMBL199411

CCCCCCCCCCCCCCCCN[C@@H](CCCCN)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOD1 Q9Y239 5/20 0.58
TLR2 O60603 2/20 0.57
SIRT6 Q8N6T7 1/20 0.57
SIRT1 Q96EB6 1/20 0.57
SLC6A5 Q9Y345 1/20 0.56
GNAI3 P08754 1/20 0.55
GNAO1 P09471 1/20 0.55
GNAI1 P63096 1/20 0.55
RRM1 P23921 1/20 0.46
FOLH1 Q04609 1/20 0.46
GGT1 P19440 1/20 0.45
GPR84 Q9NQS5 3/20 0.44
FFAR1 O14842 1/20 0.44
DPP7 Q9UHL4 1/20 0.44
FURIN P09958 1/20 0.44
MAPT P10636 1/20 0.43
LCK P06239 1/20 0.43
PPARD Q03181 1/20 0.43
ZDHHC20 Q5W0Z9 1/20 0.43
ZDHHC2 Q9UIJ5 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28385127 1.00 NOD1 (0.58) NOD1TLR2SIRT6SIRT1SLC6A5
SCHEMBL31042212 1.00 NOD1 (0.58) NOD1TLR2SIRT6SIRT1SLC6A5
SCHEMBL2050730 1.00 NOD1 (0.58) NOD1TLR2SIRT6SIRT1SLC6A5
SCHEMBL31042213 1.00 NOD1 (0.58) NOD1TLR2SIRT6SIRT1SLC6A5
SCHEMBL31050906 1.00 NOD1 (0.58) NOD1TLR2SIRT6SIRT1SLC6A5
SCHEMBL285285 1.00 NOD1 (0.58) NOD1TLR2SIRT6SIRT1SLC6A5
SCHEMBL9791228 1.00 NOD1 (0.58) NOD1TLR2SIRT6SIRT1SLC6A5
SCHEMBL7460571 1.00 NOD1 (0.58) NOD1TLR2SIRT6SIRT1SLC6A5
SCHEMBL2701831 1.00 NOD1 (0.58) NOD1TLR2SIRT6SIRT1SLC6A5
SCHEMBL28461571 1.00 NOD1 (0.58) NOD1TLR2SIRT6SIRT1SLC6A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4226918-A1 PHARMACEUTICAL SINGLE DOSAGE FORM FOR ORAL DELIVERY OF PEPTIDES Majewski, Filip (PL) 2023-08-16 EP claimed
US-20160339081-A1 Peptide Pharmaceutical for Oral Delivery UNIGENE LABORATORIES INC. 2016-11-24 US claimed
EP-0162747-B1 LYSINE ESTERS USED AS ABSORPTION ENHANCING AGENTS MERCK & CO. INC. (US) 1988-12-07 EP claimed
CN-115920000-B Modulators of complement activity RA制药公司 2025-04-25 CN disclosed
US-20250073309-A1 METHODS OF TREATMENT OF PEDIATRIC PUBERTY USING ORAL FORMULATIONS OF LEUPROLIDE ENTERIS BIOPHARMA, INC. (US) 2025-03-06 US disclosed
US-20250057771-A1 ROOM TEMPERATURE STABLE ORAL CALCITONIN FORMULATION PARK THERAPEUTICS INC (US) 2025-02-20 US disclosed
CN-118695874-A Cancer therapy with TLR7/8 agonists 阿森迪斯药物肿瘤股份有限公司 2024-09-24 CN disclosed
US-11998640-B2 Room temperature stable oral calcitonin formulation PARK THERAPEUTICS, INC. (US) 2024-06-04 US disclosed
US-20240108740-A1 THERAPEUTIC COMPOSITIONS INCLUDING SPN10 AND USES THEREOF STEALTH BIOTHERAPEUTICS INC. (US) 2024-04-04 US disclosed
US-20240059735-A1 COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF MITOCHONDRIAL MYOPATHIES STEALTH BIOTHERAPEUTICS INC. (US) 2024-02-22 US disclosed
EP-4319790-A1 METHODS OF TREATMENT OF PEDIATRIC PUBERTY USING ORAL FORMULATIONS OF LEUPROLIDE Enteris BioPharma, Inc. (US) 2024-02-14 EP disclosed
WO-2004064758-A2 IMPROVED ORAL DELIVERY OF PEPTIDES UNIGENE LABORATORIES INC. (US) 2004-08-05 WO disclosed
US-6673574-B2 PH LOWERING AGENT AND/OR PRTOEASE INHIBITOR AND AN ACID RESISTANT PROTECTIVE VEHICLE FOR TRANSPORT THROUGH THE STOMACH UNIGENE LABORATORIES INC. 2004-01-06 US disclosed
EP-1339431-A1 IMPROVED ORAL DELIVERY OF PEPTIDES USING ENZYME-CLEAVABLE MEMBRANE TRANSLOCATORS Unigene Laboratories, Inc. (US) 2003-09-03 EP disclosed
US-20030118610-A1 Oral delivery of peptides using enzyme-cleavable membrane translocators UNIGENE LABORATORIES INC. 2003-06-26 US disclosed
WO-2002043767-A1 IMPROVED ORAL DELIVERY OF PEPTIDES USING ENZYME-CLEAVABLE MEMBRANE TRANSLOCATORS UNIGENE LABORATORIES INC. (US) 2002-06-06 WO disclosed
EP-0929270-A4 ORAL PEPTIDE PHARMACEUTICAL PRODUCTS UNIGENE LAB INC (US) 2001-05-16 EP disclosed
US-6086918-A RELEASING PEPTIDE ACTIVE AGENT, WITH PH LOWERING AGENT AND AN ABSORPTION ENHANCER INTO PATIENT'S INTESTINE THROUGH MOUTH AND STOMACH UNDER PROTECTION OF AN ACID RESISTANT VEHICLE WHICH PREVENTS CONTACT BETWEEN STOMACH PROTEASE AND PEPTIDE UNIGENE LABORATORIES, INC. (US) 2000-07-11 US disclosed
EP-0929270-A1 ORAL PEPTIDE PHARMACEUTICAL PRODUCTS Unigene Laboratories, Inc. (US) 1999-07-21 EP disclosed
WO-1997033531-A1 ORAL PEPTIDE PHARMACEUTICAL PRODUCTS UNIGENE LABORATORIES, INC. (US) 1997-09-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240059735-A1 COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF MITOCHONDRIAL MYOPATHIES MTPN, CKMT1A; CKMT1B, TFAM NOD1 2495/4885TLR2 4609/4885SIRT6 2039/4885
US-20240108740-A1 THERAPEUTIC COMPOSITIONS INCLUDING SPN10 AND USES THEREOF S100A10, SPG11, TMSB10 NOD1 228/4885TLR2 2823/4885SIRT6 3248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.