SCHEMBL284620

SCHEMBL284620

CCN(CC)CCc1cccc2[nH]nnc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 7/20 0.47
HTR6 P50406 1/20 0.47
HTR2A P28223 4/20 0.40
HTR2C P28335 1/20 0.38
HTR1D P28221 2/20 0.37
MPO P05164 1/20 0.37
HRH3 Q9Y5N1 2/20 0.35
TSHR P16473 2/20 0.34
SLC6A2 P23975 1/20 0.33
CDYL Q9Y232 1/20 0.33
KDM4E B2RXH2 2/20 0.33
LMNA P02545 1/20 0.33
CHRM2 P08172 1/20 0.33
CYP3A4 P08684 1/20 0.33
ADRA2A P08913 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
DRD2 P14416 1/20 0.33
ADRA2B P18089 1/20 0.33
DRD1 P21728 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8514313 0.90 HTR1A (0.46) HTR1AHTR6HTR2AHTR1DHRH3
SCHEMBL10002573 0.87 BCHE (0.40) HTR1AHTR6HTR2AHRH3KDM4E
SCHEMBL8514417 0.86 DRD2 (0.39) HTR1AHTR6HTR2AHRH3KDM4E
SCHEMBL8510878 0.85 DRD2 (0.40) HTR1AHTR2AHRH3KDM4ELMNA
SCHEMBL8514405 0.85 DRD2 (0.40) HTR1AHTR2AHRH3KDM4ELMNA
SCHEMBL8510730 0.85 DRD2 (0.40) HTR1AHTR2AHRH3KDM4ELMNA
SCHEMBL8513372 0.85 DRD2 (0.40) HTR1AHTR2AHRH3KDM4ELMNA
SCHEMBL534964 0.85 DRD2 (0.40) HTR1AHTR2AHRH3KDM4ELMNA
SCHEMBL8512101 0.85 DRD2 (0.40) HTR1AHTR2AHRH3KDM4ELMNA
SCHEMBL8513547 0.85 DRD2 (0.40) HTR1AHTR2AHRH3KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2471896-B1 REFRIGERANT OIL FOR FREEZERS AND OPERATING FLUID COMPOSITION FOR FREEZERS JX NIPPON OIL & ENERGY CORP (JP) 2017-05-24 EP disclosed
US-9090806-B2 Refrigerant oil for freezers and operating fluid composition for freezers JX NIPPON OIL & ENERGY CORPORATION (JP) 2015-07-28 US disclosed
US-8889031-B2 Working fluid composition for refrigerator machine and refrigerating machine oil JX NIPPON OIL & ENERGY CORPORATION (JP) 2014-11-18 US disclosed
EP-2740784-A1 Refrigerant oil for freezers and operating fluid composition for freezers JX Nippon Oil & Energy Corporation (JP) 2014-06-11 EP disclosed
EP-2733192-A1 Refrigerant oil for freezers and operating fluid composition for freezers JX Nippon Oil & Energy Corporation (JP) 2014-05-21 EP disclosed
EP-2423297-B1 Hydraulic oil composition NIPPON OIL CORP (JP) 2013-06-05 EP disclosed
CN-101484560-B Refrigerator oil, compressor oil composition, hydraulic working oil composition, metal working oil composition, heat treatment oil composition, lubricating oil composition for machine tool, and lubricating oil composition NIPPON OIL CORP 2013-03-27 CN disclosed
US-8299006-B2 Compressor oil composition NIPPON OIL CORPORATION (JP) 2012-10-30 US disclosed
US-20120228541-A1 REFRIGERANT OIL FOR FREEZERS AND OPERATING FLUID COMPOSITION FOR FREEZERS JX NIPPON OIL & ENERGY CORPORATION (JP) 2012-09-13 US disclosed
US-8247360-B2 Heat treating oil composition NIPPON OIL CORPORATION (JP) 2012-08-21 US disclosed
EP-2039746-A1 REFRIGERATOR OIL, COMPRESSOR OIL COMPOSITION, HYDRAULIC FLUID COMPOSITION, METALWORKING FLUID COMPOSITION, HEAT TREATMENT OIL COMPOSITION, LUBRICANT COMPOSITION FOR MACHINE TOOL AND LUBRICANT COMPOSITION Nippon Oil Corporation (JP) 2009-03-25 EP disclosed
US-20080058235-A1 Lubricative Composition for Industrial Machinery and Equipment NIPPON OIL CORPORATION (JP) 2008-03-06 US disclosed
CN-101108996-A Refrigerating machine oil compositions NIPPON OIL CORP (JP) 2008-01-23 CN disclosed
US-20070275865-A1 Refrigerating Machine Oil NIPPON OIL CORPORATION (JP) 2007-11-29 US disclosed
US-20070257229-A1 Refrigerating Machine Oil Composition NIPPON OIL CORPORATION (JP) 2007-11-08 US disclosed
US-20070032391-A1 Refrigerating machine oil composition NIPPON OIL CORPORATION (JP) 2007-02-08 US disclosed
EP-1734103-A1 LUBRICATING OIL COMPOSITION FOR INDUSTRIAL MACHINERY AND EQUIPMENT Nippon Oil Corporation (JP) 2006-12-20 EP disclosed
CN-1826400-A Refrigerating machine oil composition NIPPON OIL CORP (JP) 2006-08-30 CN disclosed
US-5912212-A OIL WITH 3-METHYL-5-TERT-BUTYL-4-HYDROXYPHENYL FATTY ESTER, SULFUR AND PHOSPHORUS NIPPON OIL CO., LTD. (JP) 1999-06-15 US disclosed
EP-0781834-A2 Lubricating oil composition NIPPON OIL CO. LTD. (JP) 1997-07-02 EP disclosed