Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 16/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21722490 | 0.84 | ADORA2A (0.77) | ADORA2AADORA1ADORA2B | |
| SCHEMBL21730375 | 0.84 | ADORA2A (0.77) | ADORA2AADORA1ADORA2B | |
| SCHEMBL29201299 | 0.84 | ADORA2A (0.72) | ADORA2AADORA1 | |
| SCHEMBL28459169 | 0.79 | ADORA2A (0.50) | ADORA2AADORA1 | |
| SCHEMBL21722550 | 0.77 | ADORA2A (0.72) | ADORA2AADORA1ADORA2B | |
| SCHEMBL22551891 | 0.77 | ADORA2A (0.76) | ADORA2AADORA1ADORA2B | |
| SCHEMBL30175480 | 0.77 | ADORA2A (0.76) | ADORA2AADORA1ADORA2B | |
| SCHEMBL22551786 | 0.77 | ADORA2A (0.76) | ADORA2AADORA1ADORA2B | |
| SCHEMBL22551867 | 0.77 | ADORA2A (0.76) | ADORA2AADORA1ADORA2B | |
| SCHEMBL28460330 | 0.76 | ADORA2A (0.51) | ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181092-A | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-112279837-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-111747954-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2021-08-24 | — | — | CN | disclosed |
| CN-112279837-A | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2021-01-29 | — | — | CN | disclosed |
| CN-112055709-A | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2020-12-08 | — | — | CN | disclosed |
| CN-111747954-A | Pyrazine compounds and uses thereof | 迪哲（江苏）医药有限公司 | 2020-10-09 | — | — | CN | disclosed |