Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | APLNR | P35414 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.32 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | RRM1 | P23921 | 1/20 | 0.31 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12806459 | 0.70 | LPAR1 (0.49) | LPAR1POLBGAAGFERLMNA | |
| SCHEMBL30626962 | 0.70 | LPAR1 (0.49) | LPAR1POLBGAAGFERLMNA | |
| SCHEMBL18250079 | 0.69 | MTNR1A (0.47) | HTTPOLBGAAMC4RMEN1 | |
| SCHEMBL21673459 | 0.68 | KDM4E (0.41) | POLBGAAGFER | |
| SCHEMBL30178974 | 0.68 | KDM4E (0.41) | POLBGAAGFER | |
| SCHEMBL4974576 | 0.68 | KDM4E (0.41) | POLBGAAGFER | |
| SCHEMBL16564328 | 0.68 | LPAR1 (0.43) | LPAR1GAALMNA | |
| SCHEMBL7947311 | 0.66 | TSHR (0.42) | LPAR1SMN1; SMN2APLNRGAALMNA | |
| SCHEMBL1321414 | 0.66 | KDM4E (0.39) | LPAR1APLNRPOLBMEN1KMT2A | |
| SCHEMBL21472351 | 0.65 | CYP2D6 (0.53) | LPAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107849050-B | Compound (I) | 爱丁堡大学董事会 | 2020-10-13 | — | — | CN | disclosed |