Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.71 |
| ▸ | RAB9A | P51151 | 9/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.71 |
| ▸ | MEN1 | O00255 | 8/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.71 |
| ▸ | HPGD | P15428 | 4/20 | 0.71 |
| ▸ | PKM | P14618 | 3/20 | 0.71 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | GLA | P06280 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29660212 | 0.84 | NPC1 (1.00) | NPC1RAB9AKDM4EALDH1A1MEN1 | |
| SCHEMBL537905 | 0.84 | NPC1 (1.00) | NPC1RAB9AKDM4EALDH1A1MEN1 | |
| SCHEMBL537904 | 0.84 | NPC1 (1.00) | NPC1RAB9AKDM4EALDH1A1MEN1 | |
| SCHEMBL31305038 | 0.82 | NPC1 (0.89) | NPC1RAB9AKDM4EALDH1A1MEN1 | |
| SCHEMBL1086983 | 0.82 | ALDH1A1 (0.81) | NPC1RAB9AKDM4EALDH1A1MEN1 | |
| SCHEMBL1086985 | 0.82 | ALDH1A1 (0.81) | NPC1RAB9AKDM4EALDH1A1MEN1 | |
| SCHEMBL29539476 | 0.82 | ALDH1A1 (0.81) | NPC1RAB9AKDM4EALDH1A1MEN1 | |
| SCHEMBL2458502 | 0.80 | RAB9A (1.00) | NPC1RAB9AKDM4EALDH1A1MEN1 | |
| SCHEMBL7287844 | 0.80 | RAB9A (0.54) | NPC1RAB9AKDM4EALDH1A1MEN1 | |
| SCHEMBL1900921 | 0.80 | KMT2A (0.74) | NPC1RAB9AKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108950645-B | Aluminum and aluminum alloy anodic oxidation nickel-free sealing agent | 上海铝通化学科技有限公司 | 2020-10-23 | — | — | CN | disclosed |