Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | F2 | P00734 | 3/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.52 |
| ▸ | HTR6 | P50406 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 2/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5010791 | 0.88 | HPRT1 (0.54) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL29965319 | 0.81 | CA1 (0.68) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL3071825 | 0.81 | CA1 (0.68) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL547461 | 0.81 | CA1 (0.68) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL5008290 | 0.81 | ALDH1A1 (0.43) | CA1CA2CA9F2PRSS1 | |
| Water SCHEMBL4291375 | 0.80 | CA1 (0.61) | CA1CA2CA9F2PRSS1 | |
| Water SCHEMBL8193333 | 0.80 | CA1 (0.61) | CA1CA2CA9F2PRSS1 | |
| Water SCHEMBL27657904 | 0.80 | CA1 (0.61) | CA1CA2CA9F2PRSS1 | |
| Water SCHEMBL11359521 | 0.80 | CA1 (0.61) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL7175789 | 0.79 | CA1 (0.65) | CA1CA2CA9F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1471 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023067170-A1 | COMPOUNDS FOR THE TREATMENT OF MALARIA | FUNDACIÓ INSTITUT DE BIOENGINYERIA DE CATALUNYA (ES) | 2023-04-27 | — | — | WO | claimed |
| EP-1790639-B1 | SPIROCYCLIC COMPOUNDS AND THEIR USE AS CXCR4-ANTAGONISTS | ONO PHARMACEUTICAL CO (JP) | 2014-03-26 | — | — | EP | claimed |
| EP-2049502-B1 | 2,4-SUBSTITUTED QUINAZOLINES AS LIPID KINASE INHIBITORS | NOVARTIS AG (CH) | 2012-01-04 | — | — | EP | claimed |
| JP-4838934-B2 | — | — | 2011-12-14 | — | — | JP | claimed |
| US-8053457-B2 | 3-imidazolyl-indoles for the treatment of proliferative diseases | NOVARTIS AG (CH) | 2011-11-08 | — | — | US | claimed |
| US-7951816-B2 | Compound containing basic group and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2011-05-31 | — | — | US | claimed |
| JP-4642242-B2 | — | — | 2011-03-02 | — | — | JP | claimed |
| US-20100305113-A1 | Substituted Imidazopyridazines as Lipid Kinase Inhibitors | CAPRARO HANS-GEORG | 2010-12-02 | — | — | US | claimed |
| EP-1863477-B1 | 3,4-SUBSTITUTED PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF HYPERTENSION | NOVARTIS AG (CH) | 2010-11-03 | — | — | EP | claimed |
| EP-1836163-B1 | PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN | NOVARTIS AG (CH) | 2010-09-22 | — | — | EP | claimed |
| US-4582897-A | 2-AZO-4-SULFO-4-METHYLDIPHENYL SULFONE DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1986-04-15 | — | — | US | claimed |
| EP-0042357-B1 | AZO DYES, THEIR PREPARATION AND USE | CIBA-GEIGY AG (CH) | 1984-06-06 | — | — | EP | claimed |
| US-4406875-A | Radiolabeled amine compounds and their use | BYK-MALLINCKRODT CIL B.V. (NL) | 1983-09-27 | — | — | US | claimed |
| EP-0042357-A2 | Azo dyes, their preparation and use | CIBA-GEIGY AG (CH) | 1981-12-23 | — | — | EP | claimed |
| US-4292238-A | Alkylation of benzthiazole-azo-phenylamine dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1981-09-29 | — | — | US | claimed |
| WO-1980001685-A1 | RADIOLABELED AMINE COMPOUNDS AND THEIR USE | BYK MALLINCKRODT CIL BV (NL) | 1980-08-21 | — | — | WO | claimed |
| US-4146541-A | YELLOW SHADE ON POLYESTERS | CIBA-GEIGY AG (CH) | 1979-03-27 | — | — | US | claimed |
| US-4021428-A | 4-Piperidino-5-oxo-2-pyrazolines | FUJI PHOTO FILM CO., LTD. (JA) | 1977-05-03 | — | — | US | claimed |
| US-3996208-A | PENICILLINS | CIBA-GEIGY CORPORATION (US) | 1976-12-07 | — | — | US | claimed |
| US-3956339-A | 4-Pyridinio-5-pyrazolone salts, process for their preparation and their use | FUJI PHOTO FILM CO., LTD. (JA) | 1976-05-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305113-A1 | Substituted Imidazopyridazines as Lipid Kinase Inhibitors | PI4KA, PIK3CA, PIK3CB | CA1 4176/4885CA2 1974/4885CA9 4243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.