SCHEMBL547461

SCHEMBL547461

O=S(=O)(c1cccc2ccccc12)c1cccc2ccccc12

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.68
CA2 P00918 1/20 0.68
CA9 Q16790 1/20 0.68
HTR6 P50406 7/20 0.66
AKR1B1 P15121 1/20 0.56
F2 P00734 3/20 0.55
PRSS1 P07477 3/20 0.55
PRSS2 P07478 3/20 0.55
PRSS3 P35030 3/20 0.55
MAOA P21397 1/20 0.54
LOX P28300 1/20 0.54
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
LOXL2 Q9Y4K0 2/20 0.50
HCRTR1 O43613 1/20 0.49
TSHR P16473 1/20 0.47
ALPL P05186 1/20 0.47
ALPI P09923 1/20 0.47
ALPG P10696 1/20 0.47
DNMT1 P26358 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7175789 0.98 CA1 (0.65) CA1CA2CA9HTR6AKR1B1
Phosphonic Acid SCHEMBL28657855 0.89 CA1 (0.57) CA1CA2CA9HTR6AKR1B1
SCHEMBL11197940 0.88 CA1 (0.55) CA1CA2CA9HTR6AKR1B1
SCHEMBL13241574 0.88 CA1 (0.55) CA1CA2CA9HTR6AKR1B1
SCHEMBL10388568 0.88 GAA (0.69) CA1CA2CA9HTR6AKR1B1
SCHEMBL7190517 0.88 CA1 (0.60) CA1CA2CA9HTR6AKR1B1
SCHEMBL3249669 0.87 HTR6 (0.73) CA1CA2CA9HTR6AKR1B1
SCHEMBL3071825 0.85 CA1 (0.68) CA1CA2CA9HTR6AKR1B1
SCHEMBL29965319 0.85 CA1 (0.68) CA1CA2CA9HTR6AKR1B1
SCHEMBL7535415 0.84 CA1 (0.52) CA1CA2CA9HTR6AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 458 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240222600-A1 ABSORBENT GLASS MAT BATTERY CLARIOS GERMANY GMBH & CO. KG (DE) 2024-07-04 US claimed
CN-115505100-B Epoxy resin based on spirosilafluorene as framework, and preparation method and application thereof 中国石油化工股份有限公司 2024-06-28 CN claimed
CN-115505099-B Epoxy resin containing carbazole structure, and preparation method and application thereof 中国石油化工股份有限公司 2024-06-28 CN claimed
US-11936032-B2 Absorbent glass mat battery CPS TECHNOLOGY HOLDINGS LLC (US) 2024-03-19 US claimed
WO-2023020538-A1 SERIAL ORGANIC ELECTROLUMINESCENT DEVICE 清华大学 2023-02-23 WO claimed
CN-115505099-A Epoxy resin containing carbazole structure and preparation method and application thereof 中国石油化工股份有限公司 2022-12-23 CN claimed
CN-115505100-A Epoxy resin based on spirosilafluorene as skeleton and preparation method and application thereof 中国石油化工股份有限公司 2022-12-23 CN claimed
CN-111943949-B Organic compound, application thereof and organic electroluminescent device containing compound 清华大学 2022-05-20 CN claimed
EP-2481760-B1 INITIATOR SYSTEM FOR CATIONIC POLYMERIZATION AND POLYMERIZATION METHOD USING SAME CHINA PETROLEUM & CHEM CORP (CN) 2021-05-05 EP claimed
US-8577267-B2 Transparent intermediate transfer members containing zinc oxide, polyarylsulfone, and polyetheramine XEROX CORPORATION (US) 2013-11-05 US claimed
US-8343934-B2 Diverse lead compound autotaxin inhibitors UNIVERSITY OF MEMPHIS (US) 2013-01-01 US claimed
US-20120119160-A1 TRANSPARENT INTERMEDIATE TRANSFER MEMBERS CONTAINING ZINC OXIDE, POLYARYLSULFONE, AND POLYETHERAMINE XEROX CORPORATION (US) 2012-05-17 US claimed
US-20110160148-A1 Novel Diverse Lead Compound Autotaxin Inhibitors THE UNIVERSITY OF MEMPHIS RESEARCH FOUNDATION (US) 2011-06-30 US claimed
WO-2011002918-A1 NOVEL DIVERSE LEAD COMPOUND AUTOTAXIN INHIBITORS THE UNIVERSITY OF MEMPHIS RESEARCH FOUNDATION (US) 2011-01-06 WO claimed
EP-1150979-A1 HETEROARYL AMIDINES, METHYLAMIDINES AND GUANIDINES AS PROTEASE INHIBITORS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2001-11-07 EP claimed
WO-2000047578-A1 HETEROARYL AMIDINES, METHYLAMIDINES AND GUANIDINES AS PROTEASE INHIBITORS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2000-08-17 WO claimed
EP-0165388-B1 SHAPED ARTICLE AND COMPOSITE MATERIAL FOR ITS PREPARATION Dansk Eternit-Fabrik A/S (DK) 1989-09-27 EP claimed
JP-7271102-A None JP disclosed
US-4072497-A (5-Alkylureido-1,3,4-thiadiazol-2-yl-thio) acetic acid tert-butyl esters and herbicidal compositions and processes SCHERING AKTIENGESELLSCHAFT (DT) 1978-02-07 US disclosed
US-4069205-A FROM BI- OR TRI-PHENYLENE SULFIDE, AROMATIC ETHER, AND ISOPHTHALOYL OR TEREPHTHALOYL HALIDE UNIVERSITY PATENTS, INC. (US) 1978-01-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110160148-A1 Novel Diverse Lead Compound Autotaxin Inhibitors ENPP2, ABHD16A, PLAAT2 CA1 1413/4885CA2 2203/4885CA9 2249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.