Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 17/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 6/20 | 0.41 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | MET | P08581 | 3/20 | 0.39 |
| ▸ | KDR | P35968 | 3/20 | 0.39 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28341057 | 0.83 | GRM5 (0.42) | CSF1RPDGFRAPDGFRBKITFLT3 | |
| SCHEMBL28463024 | 0.83 | CSF1R (0.61) | CSF1RPDGFRAPDGFRBKITFLT3 | |
| SCHEMBL28460970 | 0.83 | GRM5 (0.50) | CSF1RPDGFRAPDGFRBFLT3MET | |
| SCHEMBL28341053 | 0.81 | CSF1R (0.61) | CSF1RPDGFRAPDGFRBKITFLT3 | |
| SCHEMBL28881795 | 0.81 | KDR (0.37) | CSF1RPDGFRAPDGFRBTGFBR1KIT | |
| SCHEMBL28470111 | 0.80 | GRM5 (0.44) | CSF1RPDGFRAPDGFRBTGFBR1KIT | |
| SCHEMBL28343616 | 0.80 | CSF1R (0.47) | CSF1RPDGFRAPDGFRBTGFBR1KIT | |
| SCHEMBL16028599 | 0.79 | LTA4H (0.43) | CSF1RPDGFRAPDGFRBTGFBR1FLT3 | |
| SCHEMBL28343624 | 0.78 | CSF1R (0.35) | CSF1RPDGFRAPDGFRBKITFLT3 | |
| SCHEMBL28341066 | 0.78 | CSF1R (0.44) | CSF1RPDGFRAPDGFRBKITFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105228620-B | N-acyl-N' - (pyridin-2-yl) ureas and analogs exhibiting anti-cancer and anti-proliferative activity | 德西费拉制药有限责任公司 | 2020-09-04 | — | — | CN | claimed |