Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30683829 | 1.00 | ADAM17 (0.53) | ADAM17ALDH1A1SLC22A1HDAC4MEN1 | |
| SCHEMBL8585754 | 0.98 | ADAM17 (0.52) | ADAM17ALDH1A1SLC22A1HDAC4MEN1 | |
| SCHEMBL27736564 | 0.94 | ADAM17 (0.56) | ADAM17ALDH1A1SLC22A1MEN1KMT2A | |
| SCHEMBL4876849 | 0.87 | ADAM17 (0.50) | ADAM17ALDH1A1MEN1KMT2AHDAC3 | |
| SCHEMBL5470501 | 0.87 | OPRM1 (0.50) | ADAM17ALDH1A1MEN1KMT2AHDAC3 | |
| SCHEMBL11855848 | 0.86 | ADAM17 (0.47) | ADAM17ALDH1A1SLC22A1MEN1KMT2A | |
| SCHEMBL7467608 | 0.86 | AKR1C1 (0.59) | ALDH1A1SLC22A1MEN1KMT2AHPGD | |
| SCHEMBL4872683 | 0.86 | ADAM17 (0.52) | ADAM17ALDH1A1SLC22A1MEN1KMT2A | |
| SCHEMBL25460832 | 0.85 | HDAC4 (0.52) | ADAM17ALDH1A1SLC22A1HDAC4MEN1 | |
| SCHEMBL8587542 | 0.85 | AKR1C1 (0.57) | ALDH1A1MEN1KMT2AHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138901-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS, DERIVATIVES THEREOF, AND RELATED METHODS OF USE | BIOGEN IDEC MA INC (US) | 2010-12-02 | — | — | WO | disclosed |
| WO-2010138901-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS, DERIVATIVES THEREOF, AND RELATED METHODS OF USE | BIOGEN IDEC MA INC (US) | 2010-12-02 | — | — | WO | disclosed |
| US-6358956-B1 | IMIDAZOLYLALKYL-1-PIPERAZINE DERIVATIVES; FARNESYL-PROTEIN AND GERANYLGERANYL TRANSFERASE INHIBITORS; ANTICARCINOGENIC AGENTS | MERCK & CO., INC. | 2002-03-19 | — | — | US | disclosed |