Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28463509 | 1.00 | CA14 (0.35) | CA14GBA1GPR88PDK2 | |
| SCHEMBL22711187 | 0.85 | CA14 (0.36) | CA14GBA1GPR88 | |
| SCHEMBL22711184 | 0.85 | CA14 (0.36) | CA14GBA1GPR88 | |
| SCHEMBL14750621 | 0.84 | MEN1 (0.34) | CA14GBA1 | |
| SCHEMBL23732293 | 0.83 | CA14 (0.35) | CA14GPR88 | |
| SCHEMBL3775087 | 0.81 | CTSK (0.37) | CA14GBA1GPR88PDK2 | |
| SCHEMBL16517171 | 0.81 | CTSK (0.37) | CA14GBA1GPR88PDK2 | |
| SCHEMBL8016966 | 0.80 | MME (0.39) | CA14 | |
| SCHEMBL1246511 | 0.80 | MME (0.39) | CA14 | |
| SCHEMBL10260946 | 0.78 | HDAC6 (0.40) | CA14GBA1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111670187-B | Beta-lactamase inhibitor and use thereof | 苏州信诺维医药科技有限公司 | 2021-04-16 | — | — | CN | disclosed |
| CN-111670187-A | Beta-lactamase inhibitor and use thereof | 苏州信诺维医药科技有限公司 | 2020-09-15 | — | — | CN | disclosed |