Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.68 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28605135 | 0.92 | KCNA3 (0.70) | KCNA3TTRMAPTMEN1ALDH1A1 | |
| SCHEMBL31495885 | 0.88 | MAPT (0.58) | KCNA3MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL29912844 | 0.85 | KCNA3 (0.60) | KCNA3TTRMEN1KMT2AEGFR | |
| SCHEMBL28581642 | 0.84 | MAOA (0.59) | KCNA3TTRMAPTMEN1ALDH1A1 | |
| SCHEMBL2266343 | 0.83 | KCNA3 (0.68) | KCNA3TTRMAPTMEN1ALDH1A1 | |
| SCHEMBL11604748 | 0.83 | KCNA3 (0.68) | KCNA3TTRMAPTMEN1ALDH1A1 | |
| SCHEMBL15471406 | 0.82 | KCNA3 (0.66) | KCNA3TTRMAPTMEN1ALDH1A1 | |
| SCHEMBL28986871 | 0.82 | KCNA3 (0.70) | KCNA3TTRMAPTMEN1ALDH1A1 | |
| SCHEMBL15859640 | 0.82 | KCNA3 (0.70) | KCNA3TTRMAPTMEN1ALDH1A1 | |
| SCHEMBL9445860 | 0.82 | KCNA3 (0.91) | KCNA3TTRMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108947910-B | Bis-benzimidazole hexafluorophosphate compound and preparation method and application thereof | 天津师范大学 | 2021-07-02 | — | — | CN | claimed |
| CN-108822130-B | Benzimidazole cyclophane and preparation method and application thereof | 天津师范大学 | 2021-03-23 | — | — | CN | claimed |
| CN-108947910-B | Bis-benzimidazole hexafluorophosphate compound and preparation method and application thereof | 天津师范大学 | 2021-07-02 | — | — | CN | disclosed |
| CN-108822130-B | Benzimidazole cyclophane and preparation method and application thereof | 天津师范大学 | 2021-03-23 | — | — | CN | disclosed |
| CN-108822130-B | Benzimidazole cyclophane and preparation method and application thereof | 天津师范大学 | 2021-03-23 | — | — | CN | disclosed |
| CN-109053689-B | Tetrabenzimidazole salt compound and preparation method and application thereof | 天津师范大学 | 2020-09-22 | — | — | CN | disclosed |
| CN-109053689-B | Tetrabenzimidazole salt compound and preparation method and application thereof | 天津师范大学 | 2020-09-22 | — | — | CN | disclosed |