SCHEMBL29912844

SCHEMBL29912844

O=C1c2cccc(OCCCBr)c2C(=O)c2c(OCCCBr)cccc21

nearest known ligand 0.60

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 1/20 0.60
ELANE P08246 8/20 0.48
EGFR P00533 1/20 0.45
PIM1 P11309 1/20 0.45
CTSG P08311 1/20 0.44
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
TTR P02766 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28605135 0.93 KCNA3 (0.70) KCNA3ELANEEGFRPIM1CTSG
SCHEMBL28463533 0.85 KCNA3 (0.68) KCNA3ELANEEGFRPIM1MEN1
SCHEMBL28581642 0.83 MAOA (0.59) KCNA3ELANEEGFRPIM1CTSG
SCHEMBL9017760 0.83 ELANE (0.67) KCNA3ELANEEGFRPIM1CTSG
SCHEMBL12332436 0.81 KCNA3 (0.58) KCNA3ELANEEGFRPIM1CTSG
SCHEMBL5105540 0.81 MAPT (0.56) KCNA3PIM1MEN1KMT2A
SCHEMBL25599533 0.79 KCNA3 (0.56) KCNA3ELANEEGFRPIM1CTSG
SCHEMBL16076555 0.77 KCNA3 (0.62) KCNA3ELANEEGFRPIM1CTSG
SCHEMBL28986871 0.77 KCNA3 (0.70) KCNA3ELANEEGFRCTSGMEN1
SCHEMBL15859640 0.77 KCNA3 (0.70) KCNA3ELANEEGFRPIM1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113117754-B Flower-shaped core-shell type magnetic mesoporous microsphere immobilized N-heterocyclic carbene cyclic palladium catalyst and preparation method and application thereof 上海理工大学 2022-10-11 CN disclosed