Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28218233 | 0.79 | KMT2A (0.41) | KMT2ASMN1; SMN2LMNAPOLBUSP2 | |
| SCHEMBL554526 | 0.78 | KMT2A (0.42) | KMT2ASMN1; SMN2LMNAPOLBUSP2 | |
| SCHEMBL554525 | 0.78 | KMT2A (0.42) | KMT2ASMN1; SMN2LMNAPOLBUSP2 | |
| SCHEMBL28005138 | 0.77 | HPGD (0.38) | KMT2ASMN1; SMN2LMNAPOLBUSP2 | |
| SCHEMBL8171695 | 0.75 | ALDH1A1 (0.42) | KMT2ASMN1; SMN2LMNAPOLBUSP2 | |
| SCHEMBL27650963 | 0.73 | LMNA (0.40) | KMT2ASMN1; SMN2LMNAPOLBUSP2 | |
| SCHEMBL28156995 | 0.73 | LMNA (0.40) | KMT2ASMN1; SMN2LMNAPOLBUSP2 | |
| SCHEMBL1815825 | 0.72 | — | — | |
| SCHEMBL2149047 | 0.72 | — | — | |
| SCHEMBL28154986 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107522659-B | 3-nitroquinoline derivative and preparation method and application thereof | 云南大学 | 2020-09-29 | — | — | CN | disclosed |