Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.59 |
| ▸ | PLK1 | P53350 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | RARB | P10826 | 3/20 | 0.53 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.53 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28462599 | 0.97 | MEN1 (0.60) | NR1H4PLK1MEN1KMT2APOLB | |
| SCHEMBL28459281 | 0.92 | MEN1 (0.67) | NR1H4PLK1MEN1KMT2APOLB | |
| SCHEMBL28459686 | 0.86 | PLK1 (0.62) | PLK1MEN1KMT2APOLBTP53 | |
| SCHEMBL28459280 | 0.83 | TP53 (0.59) | TP53TSHRPLA2G4BKDM4ERARB | |
| SCHEMBL28465310 | 0.81 | TRPV1 (0.58) | PLK1MEN1KMT2ARARB | |
| SCHEMBL24534531 | 0.81 | PLK1 (0.59) | NR1H4PLK1MEN1KMT2APOLB | |
| SCHEMBL28285215 | 0.81 | PPARA (0.64) | TP53TSHRPLA2G4BPPARARARB | |
| SCHEMBL10646907 | 0.81 | NPC1 (0.65) | NR1H4PLK1MEN1KMT2ANPC1 | |
| SCHEMBL28472389 | 0.80 | TP53 (0.54) | PLK1KMT2ATP53TSHRPLA2G4B | |
| SCHEMBL14306195 | 0.80 | PPARA (0.71) | TP53TSHRPLA2G4BPPARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111747904-A | Polyfluoroalkenyl substituted oxazole compound and preparation method thereof | 南京工业大学 | 2020-10-09 | — | — | CN | claimed |
| CN-111747904-A | Polyfluoroalkenyl substituted oxazole compound and preparation method thereof | 南京工业大学 | 2020-10-09 | — | — | CN | disclosed |