Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | PLK1 | P53350 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CCR6 | P51684 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28462599 | 0.94 | MEN1 (0.60) | MEN1KMT2APOLBPLK1MAPT | |
| SCHEMBL28463607 | 0.92 | NR1H4 (0.59) | MEN1KMT2APOLBPLK1NPC1 | |
| SCHEMBL28459686 | 0.89 | PLK1 (0.62) | MEN1KMT2APOLBPLK1MAPT | |
| SCHEMBL28463603 | 0.82 | HTT (0.60) | MEN1KMT2APOLBPLK1MAPT | |
| SCHEMBL28459416 | 0.81 | NPC1 (0.61) | MEN1KMT2APLK1SMN1; SMN2NPC1 | |
| SCHEMBL7629413 | 0.79 | L3MBTL1 (0.66) | MEN1KMT2APOLBPLK1MAPT | |
| SCHEMBL11962158 | 0.79 | PLK1 (1.00) | MEN1KMT2APOLBPLK1MAPT | |
| SCHEMBL11764689 | 0.79 | L3MBTL1 (0.60) | MEN1KMT2APOLBPLK1MAPT | |
| SCHEMBL50488 | 0.79 | GAA (0.72) | MEN1KMT2APOLBPLK1MAPT | |
| SCHEMBL28459351 | 0.78 | PLK1 (0.61) | KMT2APOLBPLK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111747904-A | Polyfluoroalkenyl substituted oxazole compound and preparation method thereof | 南京工业大学 | 2020-10-09 | — | — | CN | claimed |
| CN-111747904-A | Polyfluoroalkenyl substituted oxazole compound and preparation method thereof | 南京工业大学 | 2020-10-09 | — | — | CN | disclosed |