Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.58 |
| ▸ | PLK1 | P53350 | 5/20 | 0.57 |
| ▸ | PLK3 | Q9H4B4 | 4/20 | 0.56 |
| ▸ | THRA | P10827 | 3/20 | 0.54 |
| ▸ | THRB | P10828 | 3/20 | 0.54 |
| ▸ | RARB | P10826 | 5/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | RARA | P10276 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28459349 | 0.96 | TRPV1 (0.63) | TRPV1PLK1PLK3THRATHRB | |
| SCHEMBL28459351 | 0.90 | PLK1 (0.61) | TRPV1PLK1THRBHDAC1ALDH1A1 | |
| SCHEMBL28469389 | 0.84 | PLK1 (0.59) | TRPV1PLK1HDAC1ALDH1A1KMT2A | |
| SCHEMBL24534632 | 0.83 | PLK1 (0.60) | TRPV1PLK1PLK3THRATHRB | |
| SCHEMBL28460406 | 0.82 | THRA (0.63) | PLK1THRATHRBRARBMEN1 | |
| SCHEMBL24534900 | 0.82 | HAO1 (0.59) | TRPV1PLK1PLK3THRATHRB | |
| SCHEMBL28463607 | 0.81 | NR1H4 (0.59) | PLK1RARBMEN1KMT2A | |
| SCHEMBL28462599 | 0.81 | MEN1 (0.60) | PLK1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL10602808 | 0.79 | THRA (0.57) | TRPV1THRATHRBRARBMEN1 | |
| SCHEMBL11227652 | 0.79 | RARB (0.65) | TRPV1THRATHRBRARBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111747904-A | Polyfluoroalkenyl substituted oxazole compound and preparation method thereof | 南京工业大学 | 2020-10-09 | — | — | CN | claimed |
| CN-111747904-A | Polyfluoroalkenyl substituted oxazole compound and preparation method thereof | 南京工业大学 | 2020-10-09 | — | — | CN | disclosed |