Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | GSR | P00390 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.46 |
| ▸ | PDE2A | O00408 | 5/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3473860 | 0.80 | ALDH1A1 (0.53) | KDM4EALDH1A1GLAHPGDSMN1; SMN2 | |
| SCHEMBL3473505 | 0.80 | ALDH1A1 (0.60) | KDM4EALDH1A1GLAHPGDSMN1; SMN2 | |
| SCHEMBL28285676 | 0.80 | KDM4E (0.55) | KDM4EALDH1A1GLAHPGDSMN1; SMN2 | |
| SCHEMBL15147603 | 0.79 | KDM4E (0.58) | KDM4EALDH1A1GLAHPGDSMN1; SMN2 | |
| SCHEMBL11383178 | 0.75 | ALDH1A1 (1.00) | KDM4EALDH1A1GLAHPGDSMN1; SMN2 | |
| SCHEMBL30868870 | 0.75 | KDM4E (0.62) | KDM4EALDH1A1GLAHPGDSMN1; SMN2 | |
| SCHEMBL3978504 | 0.75 | KDM4E (0.62) | KDM4EALDH1A1GLAHPGDSMN1; SMN2 | |
| SCHEMBL12497764 | 0.75 | CYP11B1 (0.40) | KDM4EALDH1A1CYP11B1CYP11B2GSR | |
| SCHEMBL3472610 | 0.75 | KDM4E (0.50) | KDM4EALDH1A1GLAHPGDSMN1; SMN2 | |
| SCHEMBL13366929 | 0.74 | KDM4E (0.53) | KDM4EALDH1A1GLAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109988117-B | Preparation method of 3-methylquinoxaline-2 (1H) -ketone derivatives | 湖南科技学院 | 2020-09-29 | — | — | CN | disclosed |