Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.68 |
| ▸ | RAB9A | P51151 | 7/20 | 0.68 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7762322 | 0.87 | NPC1 (0.57) | NPC1RAB9ADGAT1KDM4EMAPT | |
| SCHEMBL28322058 | 0.81 | NPC1 (0.92) | NPC1RAB9ADGAT1KDM4EMAPT | |
| SCHEMBL25841445 | 0.80 | RAB9A (0.50) | NPC1RAB9AMAPTKIF11XDH | |
| SCHEMBL8744265 | 0.79 | NPC1 (0.48) | NPC1RAB9AKDM4EMAPTPIK3CD | |
| SCHEMBL4210531 | 0.79 | NPC1 (0.49) | NPC1RAB9ADGAT1KDM4EMAPT | |
| SCHEMBL13549572 | 0.77 | NPC1 (0.47) | NPC1RAB9ADGAT1MAPTPIK3CD | |
| SCHEMBL31366845 | 0.76 | SMN1; SMN2 (0.51) | NPC1RAB9AKDM4EPIK3CAHPGD | |
| SCHEMBL28606940 | 0.76 | ADORA2A (0.57) | NPC1RAB9AMAPTHPGDTSHR | |
| SCHEMBL14432249 | 0.75 | KMT2A (0.53) | NPC1RAB9AKDM4EMAPTTP53 | |
| SCHEMBL7759101 | 0.75 | KIF11 (0.54) | NPC1RAB9ADGAT1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110305112-B | Organic photoelectric material and application thereof | 武汉尚赛光电科技有限公司 | 2020-10-09 | — | — | CN | disclosed |