Ethylene

Ethylene

SCHEMBL28464372

C=C.O=C(O)C(CC(F)(F)F)CC(F)(F)F

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.35
AKR1A1 P14550 1/20 0.35
CHRM3 P20309 1/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
ADRA1A P35348 1/20 0.35
HRH1 P35367 1/20 0.35
DRD3 P35462 1/20 0.35
SLC6A3 Q01959 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CPA1 P15085 1/20 0.33
FOLH1 Q04609 7/20 0.31
HTT P42858 1/20 0.31
GRIK1 P39086 2/20 0.30
GRIK2 Q13002 2/20 0.30
SLC1A1 P43005 1/20 0.30
CYP1A2 P05177 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19825149 0.95 CHRM1 (0.38) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL19814978 0.82 SLC1A1 (0.43) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL19814981 0.82 SLC1A1 (0.43) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL2037942 0.82 CHRM1 (0.33) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL2578030 0.80 ALDH1A1 (0.39) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL500233 0.80 CA2 (0.46) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL7166147 0.80 GRIK1 (0.50) CPA1GRIK1GRIK2
SCHEMBL26755075 0.77 TDP1 (0.37) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL5389894 0.77 CHRM1 (0.62) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL703731 0.75 TET2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111735869-A Protein detection reagent and detection method 中山大学 2020-10-02 CN disclosed