Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 8/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | RAD52 | P43351 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | CFTR | P13569 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29171356 | 0.87 | BAZ2B (0.82) | BAZ2BLMNAPABPC1ATMSMN1; SMN2 | |
| SCHEMBL21114766 | 0.86 | LMNA (0.62) | BAZ2BLMNAPABPC1ATMSMN1; SMN2 | |
| SCHEMBL8228026 | 0.86 | BAZ2B (0.57) | BAZ2BLMNAPABPC1ATMSMN1; SMN2 | |
| SCHEMBL7132310 | 0.81 | LMNA (0.68) | BAZ2BLMNAPABPC1ATMSMN1; SMN2 | |
| SCHEMBL12868564 | 0.81 | LMNA (0.78) | BAZ2BLMNAPABPC1ATMSMN1; SMN2 | |
| SCHEMBL3424575 | 0.81 | BAZ2B (0.81) | BAZ2BLMNAPABPC1ATMSMN1; SMN2 | |
| SCHEMBL3477871 | 0.78 | BAZ2B (0.79) | BAZ2BLMNAPABPC1ATMSMN1; SMN2 | |
| SCHEMBL29171353 | 0.78 | BAZ2B (0.79) | BAZ2BSMN1; SMN2KMT2ACFTRKDM4E | |
| SCHEMBL28475633 | 0.78 | BAZ2B (0.79) | BAZ2BLMNAPABPC1ATMSMN1; SMN2 | |
| SCHEMBL5372790 | 0.78 | BAZ2B (0.67) | BAZ2BLMNAKDRCFTRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111757882-B | Compounds for treating, alleviating or preventing conditions associated with tau aggregates | AC免疫有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-111757882-A | 1,3,4, 5-tetrahydro-2H-pyrido [4,3-b ] indole derivatives for the treatment, alleviation or prevention of disorders associated with Tau aggregates such as alzheimer's disease | AC免疫有限公司 | 2020-10-09 | — | — | CN | disclosed |