Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 6/20 | 0.82 |
| ▸ | KDR | P35968 | 2/20 | 0.71 |
| ▸ | CFTR | P13569 | 9/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | ACHE | P22303 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5372790 | 0.90 | BAZ2B (0.67) | BAZ2BKDRCFTRUSP2CYP1A2 | |
| SCHEMBL28465408 | 0.90 | BAZ2B (0.67) | BAZ2BKDRCFTRUSP2CYP1A2 | |
| SCHEMBL28464447 | 0.87 | BAZ2B (0.64) | BAZ2BKDRCFTRALOX15HSD17B10 | |
| SCHEMBL17447456 | 0.86 | BAZ2B (0.76) | BAZ2BKDRCFTRUSP2CYP1A2 | |
| SCHEMBL12868564 | 0.86 | LMNA (0.78) | BAZ2BKDRCFTRUSP2CYP1A2 | |
| SCHEMBL30228575 | 0.85 | BAZ2B (0.74) | BAZ2BKDRCFTRUSP2CYP1A2 | |
| SCHEMBL21162488 | 0.85 | BAZ2B (0.74) | BAZ2BKDRCFTRUSP2CYP1A2 | |
| SCHEMBL3087738 | 0.85 | BAZ2B (0.70) | BAZ2BKDRCFTRUSP2CYP1A2 | |
| SCHEMBL14398035 | 0.85 | BAZ2B (0.60) | BAZ2BKDRCFTRUSP2CYP1A2 | |
| SCHEMBL3424575 | 0.84 | BAZ2B (0.81) | BAZ2BCFTRUSP2ACHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109928971-B | Aryl substituted aminotetrahydropyrans and uses thereof | 广东东阳光药业股份有限公司 | 2024-01-16 | — | — | CN | disclosed |