SCHEMBL284645

SCHEMBL284645

CCCCOC(C(=O)O)C(OCCCC)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.46
HCAR2 Q8TDS4 3/20 0.45
ALDH1A1 P00352 1/20 0.44
TSHR P16473 2/20 0.43
HPGD P15428 1/20 0.43
CA2 P00918 1/20 0.41
MAPK1 P28482 1/20 0.41
GPR84 Q9NQS5 3/20 0.40
TP53 P04637 1/20 0.40
FFAR1 O14842 1/20 0.40
PLA2G4B P0C869 2/20 0.39
MAPT P10636 1/20 0.39
LCK P06239 1/20 0.39
PPARD Q03181 1/20 0.39
ZDHHC20 Q5W0Z9 1/20 0.39
ZDHHC2 Q9UIJ5 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1196777 1.00 ATM (0.46) ATMHCAR2ALDH1A1TSHRHPGD
SCHEMBL1196078 1.00 ATM (0.46) ATMHCAR2ALDH1A1TSHRHPGD
SCHEMBL3960625 0.93 HCAR2 (0.47) HCAR2TSHRGPR84TP53FFAR1
SCHEMBL8935618 0.91 HCAR2 (0.48) HCAR2ALDH1A1TSHRGPR84TP53
SCHEMBL712622 0.91 HCAR2 (0.48) HCAR2ALDH1A1TSHRGPR84TP53
SCHEMBL5718514 0.91 HCAR2 (0.48) HCAR2ALDH1A1TSHRGPR84TP53
SCHEMBL7652872 0.91 HCAR2 (0.48) HCAR2ALDH1A1TSHRGPR84TP53
SCHEMBL453154 0.91 HCAR2 (0.48) HCAR2ALDH1A1TSHRGPR84TP53
SCHEMBL28253693 0.91 HCAR2 (0.48) HCAR2ALDH1A1TSHRGPR84TP53
SCHEMBL27575401 0.91 HCAR2 (0.48) HCAR2ALDH1A1TSHRGPR84TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 614 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108135210-A Highly uniform hydrophilic chewing gum base WM.雷格利JR.公司 2018-06-08 CN claimed
US-9149439-B2 Multi-particulate, modified-release composition SANDOZ AG (CH) 2015-10-06 US claimed
WO-2014029953-A1 HOT MELT EXTRUDED (HME) PHARMACEUTICAL COMPOSITION OF CINACALCET CIPLA LIMITED (IN) 2014-02-27 WO claimed
US-8168228-B2 Oral micropellets containing an antibiotic having an inner coating of a cellulose polymer (not enteric)and an outer coating of an enteric coating polymer; particle size of 100 to 650 mu m.; lack of bitter taste; fast dissolution; increased antibiotic bioavailability compared pellets having a matrix SANDOZ AG (CH) 2012-05-01 US claimed
US-20100179210-A1 NOVEL ENANTIOMERICALLY PURE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS Piramal Enterprises Limited (IN) 2010-07-15 US claimed
US-20100173921-A1 Antiretroviral Solid Oral Composition CIPLA LIMITED (IN) 2010-07-08 US claimed
EP-1215305-B1 Method for preparing an electroplating bath and related copper plating process IMEC (BE) 2010-05-05 EP claimed
EP-2046738-A1 ENANTIOMERICALLY PURE FLAVONE DERIVATIVES FOR THE TREATMENT OF POLIFERATIVE DISORDERS AND PROCESSES FOR THEIR PREPARATION Piramal Life Sciences Limited (IN) 2009-04-15 EP claimed
EP-1680088-B1 Taste-masked formulation comprising clarithromycin SANDOZ AG (CH) 2008-12-03 EP claimed
WO-2008017867-A2 ANTIRETROVIRAL SOLID ORAL COMPOSITION WITH AT LEAST ONE WATER INSOLUBLE POLYMER CIPLA LIMITED (IN) 2008-02-14 WO claimed
EP-1680088-A1 ANTIBIOTIC COMPOSITIONS Sandoz AG (CH) 2006-07-19 EP claimed
US-20050181052-A1 Lansoprazole microtablets PATEL SATISHKUMAR A (US) 2005-08-18 US claimed
WO-2005039536-A1 ANTIBIOTIC COMPOSITIONS SANDOZ AG (CH) 2005-05-06 WO claimed
US-20050084541-A1 Antibiotic compositions SANDOZ, AG (CH) 2005-04-21 US claimed
US-6872295-B2 Method for preparing an electroplating bath and related copper plating process INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM (IMEC) (BE) 2005-03-29 US claimed
US-20020153259-A1 Method for preparing an electroplating bath and related copper plating process INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM (IMEC) (BE) 2002-10-24 US claimed
EP-1215305-A1 Method for preparing an electroplating bath and related copper plating process INTERUNIVERSITAIR MICRO-ELEKTRONICA CENTRUM VZW (BE) 2002-06-19 EP claimed
EP-0894490-B1 Cosmetic compositions comprising a film-forming polymer OREAL (FR) 2002-01-16 EP claimed
EP-0951905-A2 Pharmaceutical compositions for programmed therapeutical coverage APR APPLIED PHARMA RESEARCH S.A. (CH) 1999-10-27 EP claimed
US-4151102-A POLYISOBUTYLENE, ESTER OF ALPHA-HYDROXY ACID, UNSATURATED ACID SWISS ALUMINIUM LTD. (CH) 1979-04-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100179210-A1 NOVEL ENANTIOMERICALLY PURE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS CDK2, CDK9, CDK1 ATM 917/4885HCAR2 3243/4885ALDH1A1 1497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.