Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL284645 | 1.00 | ATM (0.46) | ATMHCAR2ALDH1A1TSHRHPGD | |
| SCHEMBL1196078 | 1.00 | ATM (0.46) | ATMHCAR2ALDH1A1TSHRHPGD | |
| SCHEMBL3960625 | 0.93 | HCAR2 (0.47) | HCAR2TSHRGPR84TP53FFAR1 | |
| SCHEMBL8935618 | 0.91 | HCAR2 (0.48) | HCAR2ALDH1A1TSHRGPR84TP53 | |
| SCHEMBL712622 | 0.91 | HCAR2 (0.48) | HCAR2ALDH1A1TSHRGPR84TP53 | |
| SCHEMBL5718514 | 0.91 | HCAR2 (0.48) | HCAR2ALDH1A1TSHRGPR84TP53 | |
| SCHEMBL7652872 | 0.91 | HCAR2 (0.48) | HCAR2ALDH1A1TSHRGPR84TP53 | |
| SCHEMBL453154 | 0.91 | HCAR2 (0.48) | HCAR2ALDH1A1TSHRGPR84TP53 | |
| SCHEMBL28253693 | 0.91 | HCAR2 (0.48) | HCAR2ALDH1A1TSHRGPR84TP53 | |
| SCHEMBL27575401 | 0.91 | HCAR2 (0.48) | HCAR2ALDH1A1TSHRGPR84TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7229621-B2 | Method to enhance the immunogenicity of an antigen | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 2007-06-12 | — | — | US | claimed |
| EP-1071411-B1 | TOPICAL IMMUNOSTIMULATION TO INDUCE LANGERHANS CELL MIGRATION | TORREY PINES INST (US) | 2007-03-14 | — | — | EP | claimed |
| US-20160168138-A1 | PROCESS FOR THE PREPARATION OF SUVOREXANT AND INTERMEDIATES USEFUL IN THE SYNTHESIS OF SUVOREXANT | REDDY S LAB LIMTED DR (IN) | 2016-06-16 | — | — | US | disclosed |
| US-8759583-B2 | Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation | TEVA SANTE (FR) | 2014-06-24 | — | — | US | disclosed |
| US-20130066111-A1 | Process for Enantioselective Synthesis of Single Enantiomers of Modafinil by Asymmetric Oxidation | CEPHALON FRANCE (FR) | 2013-03-14 | — | — | US | disclosed |
| US-8318979-B2 | Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation | CEPHALON FRANCE (FR) | 2012-11-27 | — | — | US | disclosed |
| EP-1863760-B1 | PROCESS FOR ENANTIOSELECTIVE SYNTHESIS OF SINGLE ENANTIOMERS OF THIO-SUBSTITUTED ARYLMETHANESULFINYL DERIVATIVES BY ASYMMETRIC OXIDATION | CEPHALON FRANCE (FR) | 2012-10-03 | — | — | EP | disclosed |
| US-8183294-B2 | Process for enantioselective synthesis of single enantiomers of thio-substituted arylmethanesulfinyl derivatives by asymmetric oxidation | Cephelon France (FR) | 2012-05-22 | — | — | US | disclosed |
| US-20120123161-A1 | Process for Enantioselective Synthesis of Single Enantiomers of Modafinil by Asymmetric Oxidation | CEPHALON FRANCE (FR) | 2012-05-17 | — | — | US | disclosed |
| US-20110098505-A1 | Process for Enantioselective Synthesis of Single Enantiomers of Thio-Substituted Arylmethanesulfinyl Derivatives by Asymmetric Oxidation | CEPHALON FRANCE (FR) | 2011-04-28 | — | — | US | disclosed |
| US-7915449-B2 | Contacting the corresponding sulfur compound with complex, bas and oxidizer; oxidation; isolation | CEPHALON FRANCE (FR) | 2011-03-29 | — | — | US | disclosed |
| CN-1867544-A | Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation | CEPHALON FRANCE (FR) | 2006-11-22 | — | — | CN | disclosed |
| WO-2006097814-A1 | PROCESS FOR ENANTIOSELECTIVE SYNTHESIS OF SINGLE ENANTIOMERS OF THIO-SUBSTITUTED ARYLMETHANESULFINYL DERIVATIVES BY ASYMMETRIC OXIDATION | CEPHALON FRANCE (FR) | 2006-09-21 | — | — | WO | disclosed |
| EP-1702915-A1 | Process for enantioselective synthesis of single enantiomers of thio-substituted arylmethanesulfinyl derivatives by asymmetric oxidation | CEPHALON FRANCE (FR) | 2006-09-20 | — | — | EP | disclosed |
| US-20060205706-A1 | Process for enantioselective synthesis of single enantiomers of thio-substituted arylmethanesulfinyl derivatives by asymmetric oxidation | CEPHALON FRANCE (FR) | 2006-09-14 | — | — | US | disclosed |
| EP-1663963-A1 | PROCESS FOR ENANTIOSELECTIVE SYNTHESIS OF SINGLE ENANTIOMERS OF MODAFINIL BY ASYMMETRIC OXIDATION | CEPHALON FRANCE (FR) | 2006-06-07 | — | — | EP | disclosed |
| US-20050222257-A1 | Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation | CEPHALON, INC. (US) | 2005-10-06 | — | — | US | disclosed |
| US-20050080256-A1 | Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation | TEVA SANTE (FR) | 2005-04-14 | — | — | US | disclosed |
| WO-2005028428-A1 | PROCESS FOR ENANTIOSELECTIVE SYNTHESIS OF SINGLE ENANTIOMERS OF MODAFINIL BY ASYMMETRIC OXIDATION | CEPHALON FRANCE (FR) | 2005-03-31 | — | — | WO | disclosed |
| US-4704161-A | Photosynthesis enhancement by substituted α-hydroxybutynoic acids and derivatives | THE DOW CHEMICAL COMPANY (US) | 1987-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098505-A1 | Process for Enantioselective Synthesis of Single Enantiomers of Thio-Substituted Arylmethanesulfinyl Derivatives by Asymmetric Oxidation | SULT1A1, TST, SULT2A1 | ATM 1766/4885HCAR2 4184/4885ALDH1A1 59/4885 |
| US-20120123161-A1 | Process for Enantioselective Synthesis of Single Enantiomers of Modafinil by Asymmetric Oxidation | CYP2F1, SULT1A1, SULT2A1 | ATM 2454/4885HCAR2 2781/4885ALDH1A1 186/4885 |
| US-20130066111-A1 | Process for Enantioselective Synthesis of Single Enantiomers of Modafinil by Asymmetric Oxidation | CYP2F1, SULT1A1, SULT2A1 | ATM 2454/4885HCAR2 2781/4885ALDH1A1 186/4885 |
| US-20050222257-A1 | Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation | CYP2F1, SULT1A1, SULT2A1 | ATM 2454/4885HCAR2 2781/4885ALDH1A1 186/4885 |
| US-20060205706-A1 | Process for enantioselective synthesis of single enantiomers of thio-substituted arylmethanesulfinyl derivatives by asymmetric oxidation | SULT1A1, TST, SULT2A1 | ATM 1766/4885HCAR2 4184/4885ALDH1A1 59/4885 |
| US-20160168138-A1 | PROCESS FOR THE PREPARATION OF SUVOREXANT AND INTERMEDIATES USEFUL IN THE SYNTHESIS OF SUVOREXANT | KMO, HCRTR2, COMT | ATM 4344/4885HCAR2 321/4885ALDH1A1 1864/4885 |
| US-20050080256-A1 | Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation | MAOA, CYP2F1, MAOB | ATM 2360/4885HCAR2 2444/4885ALDH1A1 282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.