SCHEMBL28464893

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28669979	0.82	USP2 (0.61)	USP2POLBHTTGAANPSR1
	SCHEMBL13239817	0.80	USP2 (0.69)	USP2POLBHTTGAANPSR1
	SCHEMBL9009717	0.76	USP2 (1.00)	USP2POLBHTTGAANPSR1
	SCHEMBL12674416	0.74	ALDH1A1 (0.49)	USP2POLBHTTGAAALDH1A1
	SCHEMBL28663387	0.73	USP2 (0.64)	USP2POLBHTTGAANPSR1
	SCHEMBL22361763	0.72	USP2 (0.69)	USP2POLBHTTGAANPSR1
	SCHEMBL5076070	0.72	POLB (1.00)	USP2POLBHTTGAANPSR1
	SCHEMBL28470334	0.72	USP2 (0.62)	USP2POLBHTTGAANPSR1
	Phenylphosphonic Acid SCHEMBL28738307	0.71	CA2 (0.67)	USP2POLBALDH1A1MEN1KMT2A
	SCHEMBL28971881	0.71	USP2 (0.67)	USP2POLBHTTGAANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.