SCHEMBL28465115

SCHEMBL28465115

NC1=CC=C(c2ccc(N)cc2)CC1(C(F)(F)F)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.37
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PDK2 Q15119 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28055510 0.83 ALDH1A1 (0.33) ALDH1A1TP53CYP3A4TDP1
SCHEMBL41543 0.74 CYP3A4 (0.39) ALDH1A1TP53CYP3A4TDP1
SCHEMBL28702961 0.74 CYP3A4 (0.34) KIF11ALDH1A1TP53CYP3A4TDP1
Hydrochloric Acid SCHEMBL3286109 0.73 CYP3A4 (0.37) ALDH1A1TP53CYP3A4TDP1
SCHEMBL29104505 0.73 CYP3A4 (0.37) ALDH1A1TP53CYP3A4TDP1
SCHEMBL368051 0.73 CYP3A4 (0.37) ALDH1A1TP53CYP3A4TDP1
SCHEMBL3615657 0.73 CYP3A4 (0.37) ALDH1A1TP53CYP3A4TDP1
SCHEMBL2697748 0.73 CYP3A4 (0.37) ALDH1A1TP53CYP3A4TDP1
SCHEMBL844893 0.73 CYP3A4 (0.37) ALDH1A1TP53CYP3A4TDP1
Water SCHEMBL28537381 0.73 CYP3A4 (0.37) ALDH1A1TP53CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250206883-A1 POLYIMIDE PRECURSOR COMPOSITION FOR FLEXIBLE WIRING BOARDS, POLYIMIDE FILM, AND POLYIMIDE METAL LAMINATE UBE CORPORATION (JP) 2025-06-26 US disclosed
CN-111764001-B Preparation method of high-strength high-modulus polyimide fiber 东华大学 2021-06-29 CN disclosed
CN-111764001-A Preparation method of high-strength high-modulus polyimide fiber 东华大学 2020-10-13 CN disclosed
CN-105408949-B Method for manufacturing substrate for organic electronic device 株式会社LG化学 2019-08-02 CN disclosed