Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 1/20 | 0.76 |
| ▸ | HTR6 | P50406 | 13/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | UBE2N | P61088 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | HTR1F | P30939 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28471054 | 0.86 | ALK (1.00) | ALKHTR6KDM4EUBE2NL3MBTL1 | |
| SCHEMBL946516 | 0.83 | HTR6 (0.74) | ALKHTR6KDM4EUBE2NL3MBTL1 | |
| SCHEMBL28472689 | 0.82 | ALK (0.77) | ALKHTR6KDM4EUBE2NL3MBTL1 | |
| SCHEMBL2132873 | 0.80 | HTR6 (0.72) | ALKHTR6KDM4EUBE2NL3MBTL1 | |
| SCHEMBL945595 | 0.80 | HTR6 (0.72) | ALKHTR6KDM4EUBE2NL3MBTL1 | |
| SCHEMBL12700490 | 0.80 | HTR6 (0.72) | ALKHTR6KDM4EUBE2NL3MBTL1 | |
| SCHEMBL9054387 | 0.79 | HTR6 (0.67) | ALKHTR6KDM4EUBE2NL3MBTL1 | |
| SCHEMBL16375238 | 0.79 | HTR6 (0.79) | ALKHTR6KDM4EUBE2NL3MBTL1 | |
| SCHEMBL28480210 | 0.79 | HTR6 (0.63) | ALKHTR6KDM4EUBE2NL3MBTL1 | |
| SCHEMBL31366254 | 0.78 | HTR6 (0.73) | ALKHTR6KDM4EUBE2NL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111675644-B | Indole diaryl methane compound and preparation method and application thereof | 南京医科大学 | 2022-12-23 | — | — | CN | disclosed |
| CN-111675644-A | Indole diaryl methane compound and preparation method and application thereof | 南京医科大学 | 2020-09-18 | — | — | CN | disclosed |