Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 16/20 | 0.73 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | UBE2N | P61088 | 1/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | HTR1D | P28221 | 1/20 | 0.57 |
| ▸ | HTR1B | P28222 | 1/20 | 0.57 |
| ▸ | HTR1F | P30939 | 1/20 | 0.57 |
| ▸ | HTR7 | P34969 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL946516 | 0.88 | HTR6 (0.74) | HTR6ALKL3MBTL1KDM4EUBE2N | |
| SCHEMBL9239085 | 0.88 | HTR6 (0.86) | HTR6ALKKDM4EUBE2NCYP19A1 | |
| SCHEMBL31366263 | 0.88 | HTR6 (0.56) | HTR6ALKL3MBTL1KDM4EUBE2N | |
| SCHEMBL16375238 | 0.86 | HTR6 (0.79) | HTR6ALKL3MBTL1KDM4EUBE2N | |
| SCHEMBL28930519 | 0.85 | HTR6 (0.70) | HTR6ALKL3MBTL1KDM4EUBE2N | |
| SCHEMBL15250049 | 0.85 | HTR6 (1.00) | HTR6ALK | |
| SCHEMBL27936448 | 0.85 | HTR6 (0.77) | HTR6ALKL3MBTL1KDM4EUBE2N | |
| SCHEMBL31366266 | 0.83 | HTR6 (0.53) | HTR6ALKL3MBTL1 | |
| SCHEMBL28244706 | 0.82 | HTR6 (0.73) | HTR6ALKL3MBTL1KDM4EUBE2N | |
| SCHEMBL1518928 | 0.82 | HTR6 (0.72) | HTR6HTR1ADRD2HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431386-A | Synthesis method of 2'- (trifluoromethyl) -4, 5-dihydro-spiro [ furan-2, 3' -indoline ] derivative | 西北师范大学 | 2025-02-14 | — | — | CN | disclosed |