Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.48 |
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 11/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL1050579 | 1.00 | SLC15A2 (0.48) | SLC15A2GSRITGB3ITGA2BTHRB | |
| Lysine SCHEMBL28857873 | 0.99 | SLC15A2 (0.48) | SLC15A2GSRITGB3ITGA2BTHRB | |
| Histidine SCHEMBL8953768 | 0.96 | SLC15A2 (0.50) | SLC15A2GSRITGB3ITGA2BNOD1 | |
| Lysine SCHEMBL28518498 | 0.93 | GSR (0.43) | SLC15A2GSRITGB3ITGA2BTHRB | |
| SCHEMBL3948444 | 0.89 | SLC15A2 (0.59) | SLC15A2ITGB3ITGA2B | |
| Lysine SCHEMBL2196767 | 0.89 | ITGB3 (0.46) | SLC15A2GSRITGB3ITGA2BTHRB | |
| SCHEMBL30714838 | 0.89 | SLC15A2 (0.59) | SLC15A2ITGB3ITGA2B | |
| SCHEMBL3948446 | 0.89 | SLC15A2 (0.59) | SLC15A2ITGB3ITGA2B | |
| SCHEMBL30781070 | 0.88 | SLC15A2 (0.43) | SLC15A2GSRITGB3ITGA2BERAP2 | |
| SCHEMBL10525304 | 0.88 | SLC15A2 (0.43) | SLC15A2GSRITGB3ITGA2BERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118050524-A | Application of GHK tripeptide as marker in preparation of product for evaluating or assisting in evaluating skeletal muscle function | 中日友好医院(中日友好临床医学研究所) | 2024-05-17 | — | — | CN | disclosed |
| CN-114671912-B | Method for homogeneously synthesizing blue copper tripeptide with assistance of light shearing carrier | 西北工业大学 | 2024-05-14 | — | — | CN | disclosed |
| CN-117338900-A | External gel preparation for promoting diabetic wound healing and preparation method and application thereof | 中国药科大学 | 2024-01-05 | — | — | CN | disclosed |
| CN-117323407-A | Medical application of copper peptide | 深圳市迪克曼生物科技有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-116350744-A | Application of tripeptide-1 and/or tripeptide in preparation of medicine for preventing and treating chronic obstructive pulmonary disease combined with skeletal muscle dysfunction | 中日友好医院(中日友好临床医学研究所) | 2023-06-30 | — | — | CN | disclosed |
| CN-115877016-A | Application of GHK tripeptide as marker in preparation of product for evaluating or assisting in evaluating skeletal muscle function | 中日友好医院(中日友好临床医学研究所) | 2023-03-31 | — | — | CN | disclosed |
| CN-114671912-A | Method for homogeneous synthesis of blue copper tripeptide with assistance of photo-shearing carrier | 西北工业大学 | 2022-06-28 | — | — | CN | disclosed |
| CN-113975371-A | Novel application indication of tripeptide compound and copper ion chelate thereof | 中日友好医院(中日友好临床医学研究所) | 2022-01-28 | — | — | CN | disclosed |
| CN-112587650-A | Short peptide and medical application of copper ion chelate thereof | 中日友好医院(中日友好临床医学研究所) | 2021-04-02 | — | — | CN | disclosed |
| CN-112587649-A | Application of tripeptide compound and copper ion chelate thereof in preventing and treating silicosis | 中日友好医院(中日友好临床医学研究所) | 2021-04-02 | — | — | CN | disclosed |
| CN-111374901-A | Process for combining nano gold with zinc peptide | 郭于嘉 | 2020-07-07 | — | — | CN | disclosed |